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News

Headshot of Brad Bernstein

Cell Bio faculty member named Fellow of the American Association for Cancer Research Academy

April 8, 2025

Brad Bernstein has been named a Fellow of the American Association for Cancer Research Academy

Headshot of Amanda Smythers

Spiegelman Lab postdoc named a Dana-Farber Trustee Science Committee Fellow

March 27, 2025

Amanda Smythers has been named a Dana-Farber Trustee Science Committee Fellow.

Steps during the initiation of ERAD of a misfolded glycoprotein.

Rapoport lab discovers how ERAD of misfolded glycoproteins is initiated

March 17, 2025

Initiation of ERAD by the bifunctional complex of Mnl1/Htm1 mannosidase and protein disulfide isomerase

Headshot of Yingqian Chen, Silvia Huerta Lopez, Allison James and Harleen Saini

Four trainees receive Cell-Bio Gilliam Travel Awards

March 12, 2025

Yingqian Chen, Silvia Huerta Lopez, Allison James and Harleen Saini received Cell-Bio Gilliam Travel Awards

Headshot of Spyros Artavanis_Tsakonas

Cell Bio faculty member receives Wiley Prize

February 18, 2025

Professor Emeritus Spyros Artavanis-Tsakonas has been awarded the 23rd annual Wiley Prize in Biomedical Sciences for his research in Notch Signaling.

Headshot of Tom Rapoport

Cell Bio faculty member appointed to an endowed professorship

February 10, 2025

Tom Rapoport named the Don. W. Fawcett Professor of Cell Biology

Graphical abstract displaying how altered mitochondrial complex I activity leads to tumor immunogenicity

Puigserver Lab harnesses mitochondrial dysfunction for anti-cancer effects

February 4, 2025

Selective deficiency of mitochondrialrespiratory complex I subunits Ndufs4/6causes tumor immunogenicity

Insertion of the TOM70 receptor into the outer mitochondrial membrane (OMM) by the cytosolic chaperone PPID controls mitochondrial function and sustains cellular bioenergetics and cellular homeostasis under conditions of dietary lipid overloads.

Puigserver Lab identifies a chaperone-assisted mechanism controlling protein insertion into mitochondria

January 31, 2025

Chaperone-mediated insertion of mitochondrial import receptor TOM70 protects against diet-induced obesity

A schematic showing lysosomal dysfunction leading to three outcomes via nMOST: autophagy defects, mitochondrial impairments, and iron homeostasis disruption.

Harper Lab Uses Advanced Proteomic and Lipidomic Platforms to Decode Lysosomal Storage Diseases

January 31, 2025

Global cellular proteo-lipidomic profiling of diverse lysosomal storage disease mutants using nMOST

Headshot of Buyan Pan and Tajinder Ubhi

Two Cell Bio postdocs receive fellowships

January 30, 2025

Buyan Pan and Tajinder Ubhi have received American Heart Association and Helen Hay Whitney Fellowships

ZnCPT - The zinc-binding cysteine proteome (Logo)

The Chouchani Lab establishes the human zinc-binding cysteine proteome.

January 14, 2025

The human zinc-binding cysteine proteome (ZnCPT)

During transcription by RNA Polymerase II, FACT and RTF1 facilitate histone transfer and nucleosome reassembly, while SPT6 alleviates SETD2 auto-inhibition, enabling SETD2 to deposit H3K36me3 on the upstream, reassembled nucleosome.

Farnung Lab uses cryo-EM to explain why H3K36me3 is found only in gene bodies

January 13, 2025

Structural basis of H3K36 trimethylation by SETD2 during chromatin transcription

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