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Department News

Harvard Medical School Blavatnik Institute of Cell Biology logo

Liberles Lab discovers a protective hormone secreted by juvenile mice

October 9, 2013

 

In a recent report in Nature, the Liberles Lab describes their identification of a peptide pheromone secreted by sexually immature mice.

Parallel CRL adaptor Capture Proteomics graphic

Parallel Adaptor Capture: a new proteomics approach developed by the Harper Lab

October 2, 2013

Modular Cullin-RING E3 ubiquitin ligases (CRLs) use substrate binding adaptor proteins to specify target ubiquitylation.

3D reconstruction of an ER sheet connection

Rapoport Lab unveils how endoplasmic reticulum stacks are connected

August 13, 2013

The endoplasmic reticulum (ER) is a continuous membrane system consisting of the nuclear envelope and a peripheral network of membrane tubules and sheets.

Harvard Medical School Blavatnik Institute of Cell Biology logo

Yuan Lab finds that blocking macroautophagy can promote mutant p53 degradation

August 8, 2013

Accumulation of mutant p53 has been recognized as an important factor that promotes cancer progression and metastasis. 

R. King headshot

Recent faculty promotions: Randy King

July 18, 2013

Congratulations to Randy King!

Fat cells

Spiegelman Lab discovers that some fat cells can directly sense cold temperatures and activate heat generation

July 7, 2013

In an online PNAS article, the Spiegelman Lab reports on what happens when brown, white, and beige fat cells are exposed to a range of cold temperatures in vitro.

Graphic of DNA

Moazed Lab discovers how histone tails clamp nucleosomal DNA to make heterochromatin

June 19, 2013

Histones and histone-binding proteins play important role in activating and silencing eukaryotic genes. 

Steve Liberles headshot

Recent faculty promotions: Steve Liberles

June 19, 2013

Congratulations to Steve Liberles!

eople portraying the role for mTORC1 in the regulation off glutamine metabolism

Blenis Lab finds a central role for mTORC1 in the regulation of glutamine metabolism

June 17, 2013

Cancer cells require the biosynthesis of structural components for biomass production.

Pere Puigserver and Samara Reck-Peterson headshots

Recent faculty promotions: Pere Puigserver & Samara Reck-Peterson

June 2, 2013

We congratulate Pere Puigserver on his promotion to Professor of Cell Biology and Samara Reck-Peterson on her promotion to Associate Professor of Cell Biology.

S. Jeong and M. Haigis headshots

SIRT4 regulates the cellular metabolic response to DNA damage

April 29, 2013

Genomic instability and altered metabolism are key features of many cancer cells.

S. Sale and S. Artavanis-Tsakonas headshots

Notch2 genetic fate mapping reveals two previously unrecognized mammary epithelial lineages

April 29, 2013

The Notch signaling pathway links the fate of one cell to that of the next door cellular neighbor.

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