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Department News

YFP Percentage and Generations graph

Pellman Lab shows that whole genome duplication can accelerate evolutionary adaptation

March 25, 2015

Doubling the compete sets of chromosomes, or tetraploidy, occurs commonly during organismal evolution and also is frequent in disease states, such as cancer. 

Diagram of Neurons

Shi Lab uncovers a molecular program that specifies early neuronal morphology

March 11, 2015

Neurons are among the most polarized cells in nature, having emerged more than a half-billion years ago in metazoans to receive, process, and transmit information.

Eggs from African clawed frog

Gygi Lab develops methods to identify and quantify thousands of proteins in non-standard model organisms

March 9, 2015

Mass spectrometry-based proteomics enables the global identification and quantification of proteins and their posttranslational modifications in complex biological samples. 

Diagram of proteins

Moazed Lab uncovers a cellular safeguard that prevents the assembly of inactive Argonaute complexes

March 9, 2015

Small RNA molecules are familiar as negative regulators of endogenous protein-coding genes, but their more deeply conserved function is to ensure genomic stability by keeping repetitive and parasitic elements in check. 

Joan Brugge, Tomas Kirchhausen, Davie Van Vactor, Jennifer Waters, and Karen Easley headshots

Five members of the Cell Bio community profiled in the Dimensions of HMS exhibit

March 9, 2015

The Dimensions of Harvard Medical School, in the Transit Gallery of Gordon Hall, is a collection of photographs and profiles that captures a wide representation of the HMS community. 

Graphic of autoimmune destruction of insulin

Danial Lab probes the utility of phospho-BAD BH3 mimicry in restoring functional β-cell mass in diabetes

February 19, 2015

Autoimmune destruction of insulin-producing β-cells leaves individuals with type 1 diabetes (T1D) insulin dependent for life.

Reconstruction with purified components graphic

Rapoport Lab recapitulates retro-translocation of misfolded proteins with purified components

December 11, 2014

Proteins that are translocated into the endoplasmic reticulum (ER) undergo quality control so that only correctly folded proteins are moved on in the secretory pathway.

ER morphology diagram

Rapoport Lab outlines a theoretical model that explains nearly all observed ER morphologies

December 11, 2014

The endoplasmic reticulum (ER) is an important membrane-bound organelle in all eukaryotic cells.

Wade Harper and Yang Shi headshots

Cell Press designates 6 papers from 5 Cell Biology faculty members as "landmark"

December 2, 2014

Cell celebrated its 40th anniversary by revisiting "landmark" Cell publications, an esteemed list that includes six papers from five faculty members.

Dr. Randy King headshot

Randy King recognized for his excellence in teaching

November 24, 2014

Randy King, the Harry C. McKenzie Professor of Cell Biology at Harvard Medical School, has been awarded the American Association of Medical Colleges Excellence in Teaching award for his involvement and innovation in the laboratory, in the classroom and across the curriculum at HMS.  

Dr. Junying Yuan headshot

Junying Yuan named the inaugural recipient of the Elizabeth D. Hay Professorship in Cell Biology

November 17, 2014

The Elizabeth D. Hay Professorship in Cell Biology honors the legacy of Betty Hay, a pioneering figure at Harvard Medical School and in the field of cell biology. 

Graphic of dynein mechanochemical cycle

Reck-Peterson Lab reveals that Lis1 works as a molecular wedge to disrupt the dynein mechanochemical cycle

November 13, 2014

Cytoskeletal molecular motors move uni-directionally along their tracks.

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