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News

Joan Brugge headshot

Joan Brugge awarded 2016 American Cancer Society Medal of Honor

January 18, 2017

Joan Brugge was awarded the American Cancer Society Medal of Honor for Basic Research for her influential contributions to the identification of the protein encoded by the Src oncogene, as well as elucidating the fundamental aspects of events involved in the initiation and progression of cancer.

Image taken from Jennifer Waters & Talley Lambert from the Nikon Imaging Center

Team from the Nikon Imaging Center at HMS provides a comprehensive review of super-resolution microscopy

December 11, 2016

In a recent article in the Journal of Cell Biology, Jennifer Waters & Talley Lambert from the Nikon Imaging Center (NIC@HMS) review the current practical limitations and compromises that must be made when designing a super-resolution microscopy experiment.

Diagram of gene regulatory networks

Shi Lab finds that the PRC2 associated protein EPOP/C17orf96 pays a dual role in gene regulation and may contribute to cancer

December 1, 2016

Gene regulatory networks are pivotal for many biological processes.

Cell Biology Microscopy Facility

New lattice light sheet now available in the CBMF: lattice.hms.harvard.edu

November 4, 2016

The Cell Biology Microscopy Facility (CBMF) is proud to announce that their new lattice light sheet microscope is up and running! 

Diagram of mutation in mitochondrial proteins

Puigserver Lab Finds that Bromodomain Inhibition Rescues Bioenergetic Failures Caused by Mitochondrial Complex I Mutations

October 18, 2016

Mutations in mitochondrial proteins (either nuclear or mitochondrial-encoded) cause bioenergetic failures observed in mitochondrial diseases. 

Steve Liberles headshot

Steve Liberles named an HHMI Faculty Scholar and also receives NIH Director's Pioneer Award

October 13, 2016

Congratulations to Steve Liberles! 

Interphase ER and Interphase ER and proteins

Rapoport Lab demonstrates how ER shaping proteins cooperate to generate and maintain a tubular ER network

September 28, 2016

How the shape of an organelle is generated is only poorly understood, but is a fundamental question in cell biology.

Diagram of metabolic reprogramming of cancer cells

Puigserver Lab connects mitochondrial heterogeneity to metastasis

September 14, 2016

Metabolic reprogramming in cancer cells is tightly associated with tumor progression but the effect of metabolic regulatory circuits on metastasis processes is poorly understood.

John Flanagan headshot

John Flanagan receives the 2016 António Champalimaud Vision Award

September 8, 2016

John Flanagan is one of four researchers who have won this year’s António Champalimaud Vision Award, which recognizes their groundbreaking research into the connection between the eyes and the brain and its implications for novel vision therapies.

Graphic of Microglia and Oligodentrocyte

Yuan Lab discovers the role of RIPK1 in mediating axonal degeneration in amyotrophic lateral sclerosis (ALS)

August 15, 2016

Axonal degeneration is frequently observed before the death of neuronal cell bodies in patients with neurodegenerative disorders including ALS and contributes significantly to neurological disability. 

Diagram of T cell

Haigis Lab identifies a novel program of mitochondrial proteome remodeling and metabolic specialization in naïve T cell activation

July 27, 2016

To initiate an immune response against pathogens, a small number of T cells within the polyclonal repertoire need to proliferate rapidly to generate large numbers of effector cells that can clear pathogens.

Cross section of intestine

Liberles Lab deconstructs gut-to-brain signals of the vagus nerve

July 1, 2016

The vagus nerve is a key body-brain connection that monitors the respiratory, cardiovascular, and digestive systems. 

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