Structural analyses, functional characterizations and computational studies reveal the ion-translocation pathway, ion-binding sites and key residues for transport activity.
In their study in NSMB, the Shao Lab identified a mechanism that coordinates tRNA and protein quality control, in which a dedicated factor specifically cleaves off the invariant 3’-CCA from peptidyl-tRNA on stalled ribosomal complexes.
Gram-negative bacteria are among the most difficult pathogen to combat, mainly due to their unique “outer membrane” which prevents most antibiotics from entering the cell.
The Chan Zuckerberg Initiative (CZI) recently announced $17 million in funding and its selection of 17 CZI Imaging Scientists — engineers, physicists, mathematicians, computer scientists, and biologists with expertise in technology development.
