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2023-2024
DATE SPEAKER TITLE HOST (Dept) Sept 7, 2023 Vincent Tagliabracci, Ph.D. The mechanism of RNA capping by SARS-CoV-2 Tom Rapoport (Cell Bio) Sept 14, 2023 Nicholas Bellono, Ph.D. Taste by touch in octopus Jon Clardy (BCMP) Sept 29, 2023 Ali Shilatifard, Ph.D.
Epigenetic moonlighting: Histone modifiers' catalytic- independent functions in the regulation of transcription,
providing new insight for cancer therapeuticsKaren Adelman (BCMP) Oct 5, 2023 Alec Kimmelman, M.D., Ph.D. Identifying Metabolic Dependencies in Pancreatic cancer Brendan Manning (Cell Bio) Oct 26, 2023 Frank Uhlmann, Ph.D. Why do chromosomes look like chromosomes (and not like a ball of yarn)? Adrian Salic (Cell Bio) Nov 16, 2023 Anders Hansen, Ph.D. Dynamics of 3D Genome Structure and Function Brad Bernstein (Cell Bio) Nov 30, 2023 Polly Fordyce, Ph.D. Microfluidics for high-throughput and
quantitative biophysics and biochemistryNick Polizzi (BCMP) Dec 7, 2023 Elçin Ünal, Ph.D. From Unconventional Gene Regulation to Cellular Rejuvenation: Insights from Meiosis Dan Finley (Cell Bio) Jan 4, 2024 Karl Deisseroth, M.D., Ph.D. Inner Workings of Microbial Ion Channels Steve Liberles (Cell Bio) Jan 11, 2024 Cees Dekker, Ph.D. Nanotechnology for single-molecule biology: from nanopore protein sequencing
to chromosome organizationWesley Wong (BCMP) Jan 25, 2024 Judith Varner, Ph.D. PI3 Kinases and other molecules controlling macrophage-mediated
cancer immune suppressionJean Zhao (BCMP) Jan 18, 2024 Iain Cheeseman, Ph.D. Rewiring Cell Division Adrian Salic (Cell Bio) Feb 8, 2024 Brittany Adamson, Ph.D. Mapping the Cellular Determinants of
Genome Editing in Human CellJohannes Walter (BCMP) Feb 15, 2024 Elaine Fuchs, Ph.D. Tissue Stem Cells: Making Choices and Living with Them in Good Times and Bad Joan Brugge (Cell Bio) Feb 29, 2024 Kole Roybal, Ph.D. Toward the Development of
Synthetic Immunity to CancerSteve Blacklow (BCMP) Mar 7, 2024 David Pagliarini, Ph.D. Wiring mitochondria: The biochemistry and biosynthesis of coenzyme Q Nika Danial (Cell Bio) Mar 14, 2024 Juli Feigon, Ph.D. Structural biology of telomerase mechanism
and interactions at telomeresGerhard Wagner (BCMP) Mar 21, 2024 Denise Montell, Ph.D. Harnessing fundamental cell biology in Drosophila for improved treatments of cancer and neurodegenerative disease David Pellman (Cell Bio) Apr 4, 2024 Harmit Malik, Ph.D. Genetic conflicts during meiosis drive the rapid evolution of essential chromatin proteins Nipun Basrur (Liberles postdoc, Cell Bio) Apr 11, 2024 Jason Cyster, Ph.D. Multifaceted roles of heterotrimeric
G-protein signaling in immunitySun Hur (BCMP) Apr 25, 2024 Geeta Narlikar, Ph.D. ATP-dependent remodeling of hexasomes, nucleosomes and chromatin condensates Lucas Farnung (Co-hosted by Cell Bio and BCMP) May 2, 2024 Barbara Meyer, Ph.D. X-Chromosome Dosage Compensation:
A Single Molecule PerspectiveKevin Struhl (BCMP) May 6, 2024 Kevin Weeks, Ph.D. Structure-based discovery and manipulation
of new functions in large RNAsSun Hur (BCMP) May 9, 2024 Shirin Bahmanyar, Ph.D. The nuclear envelope: a paradigm for membrane dynamics and function Radhika Subramanian (Cell Bio) May 16, 2024 Jamie Spangler, Ph.D. Reprogramming the immune response
through biomolecular engineeringMeredith Skiba (Kruse Lab, BCMP) June 6, 2024 Bing Ren, Ph.D. Role of Enhancers and Chromatin Architecture
in Gene Regulation and Lineage DeterminationKaren Adelman (BCMP) June 10, 2024 Torben Heick Jensen , Ph.D. Nuclear sorting of RNA Sun Hur (BCMP) June 13, 2024 Amita Sehgal, Ph.D. Unlocking the Metabolic Mysteries of Sleep: Before and After the Zzzs Davie Van Vactor (Cell Bio) June 20, 2024 Alessandro Costa, Ph.D. Activation of a Eukaryotic Origin of
Replication Visualised by Cryo-EMJohannes Walter (BCMP) -
2022-2023
DATE SPEAKER TITLE HOST (Dept) Sep 8, 2022 Jeremy Nathans Molecular Genetic Studies of CNS Vascular Development Chen Ran (Cell Bio, Liberles Lab postdoc) Sep 22, 2022 Mike Lampson Violation of Mendel's First Law: Centromere Drive and Suppression in Meiosis Radhika Subramanian (Cell Bio) Oct 13, 2022 Jeff Gordon Developing Microbiome-directed Therapeutics for Treating Child Undernutrition Sloan Devlin (BCMP) Oct 20, 2022 Jim Wells Probing and Attacking the Cancer Surfaceome Xin Zhou (BCMP) Oct 27, 2022 Judy Lieberman Lighting a Fire: Pyroptosis in the Immune Response to Infection and Cancer Nika Danial (Cell Bio) Nov 10, 2022 Asifa Akhtar Epigenetic Regulation by Histone Acetylation at Crossroads of Metabolic Control Lucas Farnung (Cell Bio) Nov 17, 2022 John Rubenstein V-ATPase: the birth, life, death, and rebirth of a proton pump Steve Harrison (BCMP) Nov 28, 2022 (Mon) Doug Green Persister Act: Near Death Experiences in Cancer Cells Joan Brugge (Cell Bio) Dec 15, 2022 Cigall Kadoch Structure and Function of Mammalian SWI/SNF Chromatin Remodeling Complexes in Human Cancer Annie Hsieh (Cell Bio, Haigis Lab postdoc) Jan 5, 2023 Eric Schmidt Biosynthetic Potential of the Animal World BCMP Trainee Committee Jan 12, 2023 Dan Nomura Imagining Druggability using Chemoproteomic Platforms Steve Gygi (Cell Bio) Jan 19, 2023 Joe Yeeles Priming in the Eukaryotic Replisome Johannes Walter (BCMP) Jan 26, 2023 Laura Kiessling Glycans in Cell Recognition Marcia Haigis (Cell Bio) Feb 2, 2023 Babis Kalodimos The Conformational Landscape of Protein Kinases in Physiology and Disease Hari Arthanari (BCMP) Feb 9, 2023 Jochen Zimmer Building an Extracellular Matrix: Insights into Hyrluranon Synthesis and Length Control Tom Rapoport (Cell Bio) Feb 16, 2023 David Bartel Regulation of mRNA Translation and Decay Sun Hur (BCMP) Feb 23, 2023 Chantal Abergel The Concept of Virus in the Giant Virus Era Amy Lee (Cell Bio) Mar 2, 2023 Sarah Woodson Dynamics of RNA-Protein Assembly during Transcription Steve Buratowski (BCMP) Mar 16, 2023 Alanna Schepartz Delivering Proteins to the Cytosol and Nucles, for Real Sloan Devlin (BCMP) Mar 23, 2023 Charles Zuker The Body-Brain Axis Steve Liberles (Cell Bio) Apr 6, 2023 Sean Morrison The Hematopoietic Stem Cell Niche Pere Puigserver (Cell Bio) Apr 13, 2023 James Bardwell Curing Nicotine Addiction through Directed Evolution (BCMP) Apr 20, 2023 Julius Brennecke Evolution of Endogenous Retroviruses in Drosophila Danesh Moazed (Cell Bio) Apr 27, 2023 James Fraser Finding new ligands to the SARS CoV 2 Macrodomain using Fragments, Neutrons, and Entropy Nick Polizzi (BCMP) May 11, 2023 Melanie Ohi Characterizing the structural building block of caveolae - from blobs to atoms and back to blobs Sun Hur (BCMP) June 1, 2023 Alberto Kornblihtt Chromatin, transcript elongation and alternative splicing at the base of a combined therapy for spinal muscular atrophy Josefina del Marmol (BCMP) June 15, 2023 Claudio Joazerio Ribosome-associated Quality Control: Mechanisms, Evolution and Role in Disease Susan Shao (Cell Bio) June 26, 2023 Alex Marson Decoding and Reprogramming Human T Cell Circuits with CRISPR Xin Zhou (BCMP) June 29, 2023 Ibrahim Cisse Super-resolution imaging of transcription in living cells Karen Adelman (BCMP) -
2021-2022
DATE SPEAKER TITLE HOST (Dept) Sep 16, 2021 John Tesmer, PhD Structure and function of G protein-coupled receptor kinases Andrew Kruse (BCMP) Sep 23, 2021 Anthony A Hyman, PhD Condensates in physiology and disease Tobi Walther (Cell Bio) Sep 27, 2021 Samara Reck-Peterson, PhD RNA Recoding of the Intracellular Transport Machinery Radhika Subramanian (Cell Bio) Sep 30, 2021 Steve Hahn, PhD Mechanisms of transcriptional regulation and coactivator specificity Steve Buratowski (BCMP) Oct 14, 2021 Rebecca Heald, PhD Fun experiments you can only do with frogs Adrian Salic (Cell Bio) Oct 21, 2021 Victor Corces, PhD Mechanisms of transgenerational inheritance of obesity epiphenotypes Steve Buratowski (BCMP) Oct 28, 2021 Xavier Darzacq, PhD Live cells single molecule biochemistry: what can we learn by interrogating molecular interactions in their cellular context? Lucas Farnung (Cell Bio) Nov 04, 2021 Kevan Shokat, PhD Discovering and Deploying Chemical Strategies to Drug KRAS: The Formerly Undruggable Oncogene Eric Fischer (BCMP) Nov 10, 2021 Gira Bhabha, PhD How microsporidia pathogens use ballistic organelles to invade host cells Tom Rapoport (Cell Bio) Nov 18, 2021 Daniela Nicastro, PhD Probing the molecular organization of cells and organelles using cryo-electron tomography Alan Brown (BCMP) Dec 02, 2021 Job Dekker, PhD Chromosome folding throughout the cell cycle and across the tree of life David Pellman (Cell Bio) Dec 09, 2021 Jeff Gordon, MD Cancelled Sloan Devlin (BCMP) Dec 16, 2021 Elly Tanaka, PhD Cellular and molecular determinants of regeneration ability Randy King (Cell Bio) Jan 06, 2022 Rotem Sorek, PhD Rescheduled Kevin Struhl (BCMP) Jan 13, 2022 David Holtzman, MD The role of APOE in Aβ and tau mediated pathogenesis of Alzheimer’s disease John Flanagan (Cell Bio) Jan 20, 2022 John Rubenstein, PhD Rescheduled Steve Harrison (BCMP) Jan 27, 2022 Yanhui Xu, PhD Structural Insights into assembly of Mediator-bound preinitiation complex Maofu Liao (Cell Bio) Feb 03, 2022 James Bardwell, PhD Rescheduled Jean Zhao(BCMP) Feb 17, 2022 Allison Williams, PhD Rescheduled Steve Blacklow (BCMP) Feb 24, 2022 Eric N Olson, PhD New Insights into Muscle Development, Disease and Regeneration Fred Goldberg (Cell Bio) Mar 03, 2022 Sarah O'Connor, PhD Harnessing the chemistry of medicinal plants Phil Cole (BCMP) Mar 10, 2022 Anne Brunet, PhD Mechanisms of aging Brendan Manning (Cell Bio) Mar 17, 2022 Amy Keating, PhD Navigating landscapes of protein-peptide interaction specificity Tim Springer (BCMP) Mar 24, 2022 Peter Walter, PhD Targeting the Cell’s Stress Pathways for Therapeutic Benefit Bob Farese (Cell Bio) Apr 07, 2022 Lily Jan, PhD Unexpected ion channel functions Marito Hayashi (Cell Bio Trainee) Apr 14, 2022 Craig Cameron, PhD Antiviral therapy: Towards the Personal and the Precise Steve Harrison (BCMP) Apr 21, 2022 Navdeep Chandel, PhD Mitochondrial control of physiology and disease Ed Chouchani (Cell Bio) Apr 28, 2022 Roshanak Irannejad, PhD Regulation of BPCR signaling by transporters Andrew Kruse (BCMP) May 05, 2022 Rachel Klevit, PhD BARD1: Out from behind BRCA1's shadow Dan Finley (Cell Bio) June 02, 2022 Leemor Joshua-Tor A Shape-shifting Nuclease Unravels Structured RNA BCMP June 09, 2022 Brian Shoichet, PhD Following the Rabbit into Chemical Space Hari Arthanari (BCMP) June 16, 2022 Eva Nogales Functional Modules in Large Transcriptional Co-activator Complexes Davie Van Vactor (Cell Bio) June 23, 2022 David Olson, PhD Psychedelics and Related Plasticity-Promoting Neurotherapeutics Sloan Devlin (BCMP) -
2020-2021
DATE SPEAKER TITLE HOST (Dept) Sep 10, 2020 Brendan D Manning, PhD PI3K-mTOR Signaling and the Metabolic Control of Cell Growth Wade Harper (Cell Bio) Sep 25, 2020 Seychelle Vos, PhD Pause & Go: Visualizing Early Mammalian Transcription Elongation Regulation Maofu Liao (Cell Bio) Oct 01, 2020 Liang Tong, PhD Molecular insights into human pre-mRNA 3'-end processing Steve Buratowski (BCMP) Oct 15, 2020 Michael Summers, PhD Structural basis and mechanism of HIV-1 genome packaging Gerhard Wagner (BCMP) Oct 22, 2020 Russell A DeBose-Boyd, PhD UBIAD1, a Vitamin K Synthetic Enzyme that Moonlights as Regulator of HMG CoA Reductase Degradation and Cholesterol Synthesis Tom Rapoport (Cell Bio) Nov 05, 2020 Eric N Olson, PhD New Insights into Muscle Development, Disease and Regeneration Fred Goldberg (Cell Bio) Nov 12, 2020 Titia de Lange, PhD The role of CST/Pola/primase at telomeres and DSBs Joe Loparo (BCMP) Dec 03, 2020 Mande Holford, PhD Venom Attacks Cancer Jon Clardy (BCMP) Dec 17, 2020 Anja Groth, PhD Chromatin Replication and Epigenome Maintenance Steve Buratowski (BCMP) Jan 07, 2021 Alejandro Sánchez Alvarado, PhD Understanding the source of regenerative potential in animals Spyros Artavanis-Tsakonas (Cell Bio) Jan 14, 2021 Mark Dawson, PhD Identifying non-genetic features of malignant clonal dominance at single cell resolution Karen Adelman (BCMP) Jan 21, 2021 Zuzana Tothova, MD, PhD Biology and Therpeutic Targeting of Cohesin Mutations in Myeloid Malignancies Joan Brugge (Cell Bio) Jan 28, 2021 Jonathan Javitch, MD, PhD Single-molecule FRET to study the organization and dynamics of receptors and transporters Andrew Kruse (BCMP) Feb 04, 2021 Vanessa Ruta, PhD Theme and Variations: Mechanisms of Behavioral Evolution Steve Liberles (Cell Bio) Feb 11, 2021 Genevieve Almouzni, PhD Histone H3 variants and partners in the nucleus Karen Adelman (BCMP) Feb 18, 2021 Olivia Rissland, PhD Destruction of Maternally Deposited RNA Binding Proteins during Embryogenesis Susan Shao (Cell Bio) Feb 25, 2021 Sonya Neal, PhD Rhomboid pseudoprotease Dfm1 ERADicates multi-spanning membrane substrates Steve Blacklow (BCMP) Mar 05, 2021 Wendy Bickmore, PhD The role of spatial proximity in genome regulation Lucas Farnung (Cell Bio) Mar 11, 2021 Robert Tjian, PhD From Biochemistry to Live Cell Single Molecule Imaging: Shifting Paradigms in Transcriptional Control Mechanisms BCMP Trainee Committee Mar 18, 2021 Ramesh Shivdasani, MD, PhD Remembrance of Things Past David Pellman (Cell Bio) Mar 25, 2021 Scott Blanchard, PhD Variant Ribosomal RNA Alleles Are Conserved, Exhibit Context-Specific Expression and have the potential to Regulate Gene Expression Sun Hur (BCMP) Mar 30, 2021 Navdeep Chandel, PhD Cancelled Ed Chouchani (Cell Bio) Apr 01, 2021 Dan Littman, MD, PhD Networking of microbiota and the immune and nervous systems in homeostasis and disease Jean Zhao (BCMP) Apr 08, 2021 Bil Clemons, PhD A detailed look at tail-anchored membrane protein targeting - from opisthokonts to protists to plants Steve Harrison (BCMP) Apr 15, 2021 Karolin Luger, PhD Unfinished business: nucleosome assembly and remodeling Danesh Moazed (Cell Bio) Apr 22, 2021 M. Madan Babu, PhD Data Science Approaches to GPCR Signaling Hari Arthanari (BCMP) Apr 29, 2021 Karen Oegema, PhD Lessons from an organelle knockout Randy King (Cell Bio) May 06, 2021 Elizabeth Villa, PhD Opening Windows into the Cell: Bringing Structure to Cell Biology with Cryo-electron tomography Steve Blacklow (BCMP) May 17, 2021 Helen Hobbs, MD Fatty liver disease: from ancestry to biochemistry Tobi Walther (Cell Bio) May 20, 2021 Alanna Schepartz, PhD Cancelled Sloan Devlin (BCMP) May 27, 2021 Carlos Bustamante, PhD Ribosomes shift into low gear in response to stable mRNA secondary structures Danesh Moazed (Cell Bio) Jun 03, 2021 Michael Snyder, PhD Big Data, Health and COVID-19 Kevin Struhl (BCMP) Jun 10, 2021 Alex Schier, PhD Cancelled Davie Van Vactor (Cell Bio) -
2019-2020
DATE SPEAKER TITLE HOST (Dept) Sep 12, 2019 Ailong Ke, PhD From Mechanism and Structural Insights to Applications for CRISPR-Cas3 Hao Wu (BCMP) Sep 19, 2019 Rachel Green, PhD Collided ribosomes function as a hub for the regulation of protein synthesis Susan Shao (Cell Bio) Sep 26, 2019 Ning Zheng, PhD Targeting Ubiquitin Ligases: Themes and Variations Eric Fischer (BCMP) Oct 2, 2019 Virginijus Šikšnys, PhD Mining CRISPR-Cas diversity: Cas9s and beyond Adrian Salic (Cell Bio) Oct 10, 2019 James Munro, PhD Single-molecule conformational-change imaging of viral glycoproteins labeled with non-canonical amino acids Tim Springer (BCMP) Oct 31, 2019 Julie Theriot, PhD Cooperation, Competition and Conviction in Decision-Making for Motile Cells Randy King (Cell Bio) Nov 7, 2019 Jian Payandeh, PhD TBA Andrew Kruse (BCMP) Nov 14, 2019 Brenda Schulman, PhD How a ubiquitin-like protein brings ubiquitylation to life Bob Farese (Cell Bio) Nov 21, 2019 Jin Zhang, PhD Illuminating the Biochemical Activity Architecture of the Cell Phil Cole (BCMP) Dec 5, 2019 Daniel Gerlich, PhD Mechanics of nuclear assembly Tomas Kirchhausen (Cell Bio) Dec 12, 2019 Cori Bargmann, PhD Organizing behavior across timescales Tim Springer (BCMP) Jan 9, 2020 Heran Darwin, PhD Regulating the Regulation by the Pup-Proteasome System in Mycobacterium tuberculosis Dan Finley (Cell Bio) Jan 16, 2020 James Berger, PhD (Un?)structural mechanisms for initiating DNA Replication Steve Harrison (BCMP) Jan 23, 2020 Olga Boudker, PhD Toward development of activators of glutamate transporters Maofu Liao (Cell Bio) Jan 30, 2020 David Cortez, PhD Replicating damaged DNA: A new story about an ancient mechanism Johannes Walter (BCMP) Feb 6, 2020 Hongtao Yu, PhD Folding the Genome by Cohesin David Pellman (Cell Bio) Feb13, 2020 Eranthie Weerapana, PhD Chemical-proteomic strategies to investigate reactive cysteines Sara Buhrlage (BCMP) Feb 24, 2020 Vishva Dixit, MD Shedding light on Ubiquitin Modification in Neurodegeneration and Cancer Alexandra Whiteley (Finley Lab) Feb 27, 2020 Ben Garcia, PhD Quantitative Proteomics for Understanding Cancer Epigenetics Phil Cole (BCMP) -
2018-2019
DATE SPEAKER TITLE HOST (Dept) Sep 20, 2018 Hiten D Madhani, MD, PhD Musings on the mesmerizing mystery of the missing methylase in a menacing meningitis microbe Yang Shi (Cell Bio) Oct 3, 2018 Bernd Bukau, PhD The busy life of nascent chains revealed by ribosome profiling: how newly synthesized proteins make it to the native state Wade Harper (Cell Bio) Nov 1, 2018 Kikue Tachibana-Konwalski, PhD How the Genome is Reorganized during Zygotic Reprogramming to Totipotency David Pellman (Cell Bio) Nov 15, 2018 Tony Hunter, PhD New signal transduction targets in cancer therapy Fred Goldberg (Cell Bio) Dec 6, 2018 Mark Krasnow, MD, PhD Lung stem cells, their niches, and cancer at single cell resolution Steve Liberles (Cell Bio) Dec 13, 2018 Agnel Sfeir, PhD Maintaining our genomes: nuclear and mitochondrial Joe Loparo (BCMP) Dec 20, 2018 Rudolf Jaenisch, PhD Stem cells and epigenetic regulation in development and disease Danesh Moazed (Cell Bio) Jan 10, 2019 Thomas Langer, PhD Proteolytic control of mitochondrial plasticity Tobi Walther (Cell Bio) Jan 17, 2019 Taekjip Ha, PhD DNA Biophysics in Chromatin Function & Cellular Mechanics Tim Springer (BCMP) Jan 24, 2019 Nieng Yan, PhD How is electrical signal generated? Structural and mechanistic investigations of Nav channels Maofu Liao (Cell Bio) Jan 31, 2019 Lori Passmore, PhD The end of the message: Mechanistic Insights into the mRNA poly(A) tail machinery Steve Buratowski (BCMP) Feb 7, 2019 Stephen Quake, PhD The Cell is a Bag of RNA Tomas Kirchhausen (Cell Bio) Feb 14, 2019 Chris Voigt, PhD Systematic Discovery of Molecules Produced by the Human Microbiome, and Engineered Microbial Interventions Jon Clardy/Sloan Devlin (BCMP) Feb 21, 2019 Jack Szostak, PhD The Origin of Cellular Life Tom Rapoport (Cell Bio) Feb 28, 2019 Cynthia Wolberger, PhD The role of H2B ubiquitination in histone methylation and nucleosome dynamics Phil Cole (BCMP) Mar 7, 2019 Manajit Hayer-Hartl, PhD Cellular Machineries for the Biogenesis and Condensate Formation of RuBisCO: the Most Abundant Protein in Nature Susan Shao (Cell Bio) Mar 14, 2019 Demet Arac, PhD Cellular Communication via Adhesion Andrew Kruse (BCMP) Mar 28, 2019 Simon Boulton, PhD Single molecule analysis of homologous recombination Johannes Walter (BCMP) Apr 11, 2019 John Diffley, PhD How our genomes are copied Johannes Walter (BCMP) Apr 24, 2019 Christopher Vakoc, MD, PhD Novel transcription factor dependencies in cancer BCMP Trainee Committee Apr 29, 2019 Cynthia Kenyon, PhD The Plasticity of Aging Kevin Struhl (BCMP) May 2, 2019 Juergen Knoblich, PhD Cerebral organoids: modelling human brain development and tumorigenesis in stem cell derived 3D culture John Flanagan (Cell Bio) May 16, 2019 Anjana Rao, PhD TET methylcytosine oxidases, cell lineage specification and cancer Adrian Salic (Cell Bio) May 23, 2019 Dario Alessi, PhD Control of Rab GTPases by the LRRK2 protein kinase Nathanael Gray (BCMP) May 30, 2019 Baljit Khakh, PhD Cells that Tile Your Brain: astrocyte roles in neural circuits Steve Liberles (Cell Bio) Jun 6, 2019 David Eisenberg, PhD Reversible amyloid-like fibrils formed by the interactions of low-complexity protein domains Gerhard Wagner (BCMP) Jun 14, 2019 Karen Vousden, PhD Metabolic control of ROS and tumour progression Joan Brugge (Cell Bio) -
2017-2018
DATE SPEAKER TITLE HOST (Dept) Sep 7, 2017 Abby Dernburg, PhD Counting to One: Meiotic crossover control through a liquid crystalline interface between chromosomes Danesh Moazed (Cell Bio) Sep 14, 2017 William Sellers, MD Linking the discovery of cancer vulnerabilities to therapeutic development Steve Blacklow (BCMP) Sep 28, 2017 Sean Brady, PhD Watch your step, there is new chemistry everywhere. Jon Clardy (BCMP) Oct 25, 2017 Alex Stark, PhD Decoding Transcriptional Regulation in Drosophila Karen Adelman (BCMP) Nov 9, 2017 Tracy Handel, PhD Structure, Activation and Inhibition of Chemokine Receptors Andrew Kruse (BCMP) Nov 16, 2017 Arshad Desai, PhD New Horizons for the Chromosome Segregation Machinery David Pellman (Cell Bio) Nov 30, 2017 John Lis, PhD Dissecting Molecular Mechanisms of Transcription & Its Regulation In Cells Karen Adelman (BCMP) Dec 7, 2017 John A G Briggs, PhD Determining the structures of coated vesicles and enveloped viruses “in situ" using Cryo-electron tomography Maofu Liao (Cell Bio) Dec 14, 2017 Elaine Ostrander, PhD Dog Genes Tell Surprising Tales: Genetic Origins and Diversity of Dog Breeds Kevin Struhl (BCMP) Jan 18, 2018 Andrea Musacchio, PhD Reconstitution of (very small parts of) cell division Danesh Moazed (Cell Bio) Jan 25, 2018 Alex Dunn, PhD Mechanosensing at cell-cell and cell-matrix adhesions Tim Springer (BCMP) Feb 1, 2018 Ruth Lehmann, PhD Protecting Immortality: Germline Mitochondrial Inheritance and Function Davie Van Vactor (Cell Bio) Feb 8, 2018 Kathrine Henzler-Wildman, PhD NMR insights into the transport mechanism of the small multi drug efflux pump, EmrE Steve Blacklow (BCMP) Feb 15, 2018 Gabriel Waksman, FMedSci, FRS Structural and molecular biology of type IV secretion systems in Gram-negative bacteria Tom Rapoport (Cell Bio) Feb 22, 2018 David Agard, PhD Protein folding as an allosteric strategy: the yin and yang of chaperone-mediated client activation BCMP Trainee Committee Mar 1, 2018 Fred Hughson, PhD Chaperoning SNARE assembly to control membrane fusion Susan Shao (Cell Bio) Mar 8, 2018 Carolyn Bertozzi, PhD Targeting glyco-immune checkpoints for cancer therapy Bob Farese & Tobi Walther (Cell Bio) Mar 15, 2018 James Haber, PhD Stability and Instability in the Repair of a Broken Chromosome Johannes Walter (BCMP) Mar 22, 2018 Patrick Cramer, PhD Transcription of the genome – from molecular movies to regulatory systems Sun Hur (BCMP) Mar 29, 2018 Ruslan Medzhitov, PhD Cellular Ecology Adrian Salic (Cell Bio) Apr 12, 2018 Daniel Fletcher, PhD Mind the gap: Physical segregation of proteins at cell-cell interfaces Susan Shao (Cell Bio) Apr 19, 2018 Michael Rape, PhD The other code: ubiquitylation and its roles in neuronal differentiation and survival Eric Fischer (BCMP) Apr 26, 2018 Huda Zoghbi, MD Equilibrium in the brain: Lessons from a balance disorder Spyros Artavanis-Tsakonas (Cell Bio) May 3, 2018 Hopi Hoekstra, PhD The genetic basis of parental care Kevin Struhl (BCMP) May 10, 2018 David Julius, PhD Natural Products as Probes of the Pain Pathway: Exploiting Toxins to Understand Gut Feelings Tomas Kirchhausen (Cell Bio) May 17, 2018 Lewis Kay, PhD Seeing the invisible by NMR spectroscopy: An application to p97 Gerhard Wagner (BCMP) May 31, 2018 Benjamin F Cravatt, PhD Activity-based proteomics – protein and ligand discovery on a global scale Heeseon An (Cell Bio Trainee) Jun 7, 2018 Melina Schuh, PhD New insights into aneuploidy in mammalian oocytes Randy King (Cell Bio) Jun 21, 2018 Diana Bautista, PhD Molecular mechanisms of itch, touch and pain. Stephen Liberles (Cell Bio) -
2016-2017
DATE SPEAKER TITLE HOST (Dept) Sep 15, 2016 David Liu, PhD Protein Evolution and Engineering to Enable Biotechnology and Novel Therapeutics Sloan Devlin (BCMP) Sep 22, 2016 Dame Carol Robinson, DBE FRS FMedSc Mass spectrometry - its roles in structural biology and drug discovery Wade Harper (Cell Bio) Sep 29, 2016 Bryan Roth, MD, PhD Structure-guided and structure-inspired GPCR drug discovery Andrew Kruse (BCMP) Oct 6, 2016 Ardem Patapoutian, PhD How do you feel? Ion channels that feel the force Steve Liberles (Cell Bio) Oct 27, 2016 Joseph (Jody) Puglisi, PhD The molecular choreography of translation Andrew Kruse (BCMP) Nov 3, 2016 Jodi Nunnari, PhD Mitochondrial Behavior Nika Danial (Cell Bio) Nov 9, 2016 Michael Elowitz, PhD Design principles for signaling, memory, and cell state control pathways in mammalian cells Danesh Moazed (Cell Bio) Nov 17, 2016 Pamela Bjorkman, PhD A Molecular Arms Race: The Immune System Versus HIV Piotr Sliz (BCMP) Dec 1, 2016 Rama Ranganathan, PhD Protein mechanics: the link between structure, function and evolvability William Shih (BCMP) Jan 9, 2017 David Baker, PhD Post-Evolutionary Biology: Design of novel protein structures, functions and assemblies Eric Fischer (BCMP) Jan 12, 2017 Sjors Scheres, PhD How cryo-EM is revolutionising structural biology: the structure of human gamma-secretase as an example Maofu Liao (Cell Bio) Jan 26, 2017 Andrew Dillin, PhD Orchestrating aging across a troubled soma Tobi Walther (Cell Bio) Feb 2, 2017 Clifford Brangwynne, PhD RNA/protein droplets: Moving through intracellular phase space Piotr Sliz (BCMP) Feb 16, 2017 Adam Frost, MD, PhD How do mitochondria divide? A fresh look at dynamin-family GTPases Steve Blacklow (BCMP) Feb 23, 2017 Daniel Herschlag, PhD Adventures in the RNA World, Past, Present and Future Matt Sonnett (Cell Bio Trainee) Mar 2, 2017 K. Dane Wittrup, PhD Synergistic Innate and Adaptive Immunotherapy for Cancer Andrew Kruse (BCMP) Mar 9, 2017 Roy Parker, PhD RNP Granules in Health and Disease Wade Harper (Cell Bio) Mar 16, 2017 Daniel Rosenbaum, Structure-function of integral membrane receptors and transporters involved in human disease BCMP Trainee Committee Mar 23, 2017 Elena Conti, PhD The RNA exosome - ribosome connection: coupling the RNA degradation and translation machineries Tom Rapoport (Cell Bio) Mar 30, 2017 Ron Breaker, PhD Discovering and Drugging Ligand-binding Riboswitches Richard Gregory (BCMP) Apr 6, 2017 David Ron, MD Short-term regulation of protein folding homeostasis in the endoplasmic reticulum Susan Shao (Cell Bio) Apr 13, 2017 Lewis Cantley, PhD PI 3-Kinase and Cancer Metabolism Jon Clardy (BCMP) Apr 21, 2017 Judith Frydman, PhD Proteostasis function and dysfunction: the delicate art of maintaining a healthy proteome Fred Goldberg (Cell Bio) Apr 27, 2017 Karlene Cimprich, PhD The Causes and Consequences of Replication Stress Johannes Walter (BCMP) May 4, 2017 Gia Voeltz, PhD Unraveling the mechanism of ER-associated organelle division Bob Farese (Cell Bio) May 11, 2017 Michael Yaffe, MD, PhD Using Systems Biology of Signaling to Improve Cancer Treatment Jean Zhao (BCMP) May 18, 2017 Sue Biggins, PhD Reconstituting kinetochore functions in vitro Danesh Moazed (Cell Bio) Jun 1, 2017 Tony Hyman, PhD biomolecular condensates, organizers of cellular biochemistry Tomas Kirchhausen (Cell Bio) Jun 8, 2017 Sebastian Seung AI and the connectome BCMP Trainee Committee Jun 15, 2017 Dyche Mullins, PhD Heraclitus and the Cytoskeleton: Physics of self-assembling materials David Pellman (Cell Bio) -
2015-2016
DATE SPEAKER TITLE HOST (Dept) Sep 10, 2015 Bradley Bernstein MD, PhD Cancer stem cells and drug resistance mechanisms in glioblastoma Andrew Lassar (BCMP) Sep 17, 2015 Pier Paolo Pandolfi, MD, PhD The Non-Coding RNA revolution in biomedical research Marcia Haigis (Cell Bio) Sep 21, 2015 Karen Adelman PhD Controlling transcription elongation of coding and non-coding RNAs Richard Gregory (BCMP) Oct 1, 2015 Gerd A. Blobel, MD, PhD Propagating transcriptional patterns through mitosis David Pellman (Cell Bio) Oct 8, 2015 Jeannie Lee, MD, PhD X inactivation as a model for Epigenetic regulation by long Noncoding RNA Kevin Struhl (BCMP) Oct 22, 2015 Gerald Crabtree, MD Chromatin regulation: New methods and new concepts from the genomics of human disease Cell Biology Postdoc Committee Nov 12, 2015 Christopher D. Lima, PhD Ubiquitin-like proteins: From conjugation to recognition Wade Harper (Cell Bio) Dec 3, 2015 Rick Young, PhD Control of Gene Expression Programs Joan Brugge (Cell Bio) Dec 10, 2015 Christine Mayr, MD, PhD Alternative 3'UTRs mediate protein-protein interactions and regulate protein localization and protein functions Steve Buratowski (BCMP) Dec 17, 2015 K. Christopher Garcia, PhD Tuning cell surface receptor signaling through ligand engineering: dimeric receptors versus GPCR Adrian Salic (Cell Bio) Jan 7, 2016 Angelika Amon, PhD The Causes and Consequences of Aneuploidy Johannes Walter (BCMP) Jan 14, 2016 Anna Pyle, PhD The molecular mechanism of RNA detection by the RIG-I antiviral sensor: new insights into nanomechanical function and immune modulation Tom Rapoport (Cell Bio) Jan 21, 2016 Taekjip Ha, PhD Mechanobiology at the Single Molecule Level Steve Blacklow (BCMP) Jan 28, 2016 Jared Rutter, PhD Mitochondria, Metabolism and Cellular Decisions: Entwined in Health and Disease Nika Danial (Cell Bio) Feb 4, 2016 Nenad Ban, PhD Beyond the prokaryotic ribosome: structural and functional insights into eukaryotic and mitochondrial ribosomes Piotr Sliz (BCMP) Feb 18, 2016 Phil Sharp, PhD The functions of small and large non-coding RNAs in gene regulation Richard Gregory (BCMP) Feb 25, 2016 Jennifer Lippincott-Schwartz, PhD Navigating the cellular landscape through new imaging technologies Tobi Walther & Bob Farese (Cell Bio) Mar 3, 2016 Ting Wu, PhD Space and Time: Chromosomes at super-resolution and a 300 year old mystery Jean Zhao (BCMP) Mar 10, 2016 Eva Nogales, PhD Visualizing structure and function of large molecular assemblies by cryo-EM Maofu Liao (Cell Bio) Mar 17, 2016 Nahum Sonenberg, PhD Translational control of cancer and autism Gerhard Wagner (BCMP) Mar 24, 2016 Christine Jacobs-Wagner, PhD Intracellular partitioning and patterning: Lessons from tiny cells David Pellman (Cell Bio) Mar 31, 2016 Leslie Vosshall, PhD Building a mosquito sensory system to hunt humans BCMP Trainee Committee Apr 14, 2016 Harry Noller, PhD RNA Mechanics and Translation Steve Harrison (BCMP) Apr 28, 2016 Michael Rosbash, PhD The Circadian Clock: Connections to Neuronal Function and RNA Kevin Struhl (BCMP) May 5, 2016 Eric Betzig, PhD Imaging Life at High Spatiotemporal Resolution Tom Kirchhausen (Cell Bio) May 12, 2016 Brian Shoichet, PhD Structure-based discovery of new chemotypes with new GPCR phamacology Andrew Kruse (BCMP) May 19, 2016 Andreas Martin, PhD Constructed to Deconstruct: The 26S proteasome as a coordinated degradation machine Fred Goldberg (Cell Bio) May 23, 2016 Yamuna Krishnan, PhD DNA nanodevices to measure protein activity in vivo Jon Clardy (BCMP) Jun 9, 2016 Anne Brunet, PhD Epigenetic and metabolic regulation of aging Yang Shi (Cell Bio) Jun 16, 2016 Dirk Görlich, PhD Transport selectivity of nuclear pore complexes Tom Rapoport (Cell Bio) -
2014-2015
DATE SPEAKER TITLE HOST (Dept) Sep 11, 2014 Rebecca Heald, PhD Mechanisms of mitosis and size control in Xenopus Davie Van Vactor (Cell Bio) Sep 25, 2014 Russell DeBose-Boyd, PhD Regulation of cholesterol synthesis through ER-associated degradation Tom Rapoport (Cell Bio) and HMS Office for Diversity Inclusion and Community Partnership Oct 9, 2014 James Bardwell, PhD New Chaperone Discovery Tom Rapoport (Cell Bio) Oct 30, 2014 Catherine Drennen, PhD Shake, Rattle, and Roll: Capturing Snapshots of Metalloenzymes in Action Steve Blacklow (BCMP) Nov 13, 2014 Thomas Schwartz, PhD Taming a Monster: Toward the Structure of the Nuclear Pore Complex Piotr Sliz (BCMP) Nov 20, 2014 Frederic de Sauvage, PhD Targeting the Hedgehog Pathway in Cancer: From Bench to Clinic Adrian Salic (Cell Bio) Dec 4, 2014 Juli Feigon, PhD To be announced Gerhard Wagner (BCMP) Dec 10, 2014 Ronald D. Vale, PhD Reconstituting T cell Signaling Samara Reck-Peterson (Cell Bio) Dec 18, 2014 Craig Peterson, PhD Chromatin dynamics and transcriptional homeostasis Steve Buratowski (BCMP) Jan 8, 2015 Brendan D. Manning, PhD Metabolic control of cell growth by the TSC-mTOR signaling network Danesh Moazed (Cell Bio) Jan 15, 2015 Robert T. Sauer, PhD Machines of protein destruction Stephen Harrison (BCMP) Jan 22, 2015 Scott Emr, PhD Sorting out membrane traffic: Ubiquitin-mediated membrane protein quality control and sorting systems Wade Harper (Cell Bio) Jan 29, 2015 Judith Campisi, PhD Cancer and aging: Rival demons? Andrew Lassar (BCMP) Feb 5, 2015 Denise Montell, PhD Life, death, and resurrection at the cellular level Joan Brugge (Cell Bio) Feb 26, 2015 Job Dekker, PhD Two ways to fold the genome Kevin Struhl (BCMP) Mar 5, 2015 Mark Von Zastrow, MD, PhD Endocytic membrane traffic and receptor-mediated cellular signaling Tom Kirchhausen (Cell Bio) Mar 12, 2015 Graham C. Walker, PhD Translesion DNA Polymerases: From Cancer Chemotherapy to Bactericidal Antibiotics Joseph Loparo (BCMP) Mar 19, 2015 Michael K. Rosen, PhD Physical mechanisms of cell organization on micron length scales David Pellman (Cell Bio) Mar 26, 2015 Robert H. Singer, PhD Imaging the regulation of single mRNA molecules in living cells BCMP Trainee Committee Apr 2, 2015 Ning Zheng, PhD Driving protein deubiquitination with propellers Dan Finley (Cell Bio) Apr 9, 2015 Michelle Wang, PhD Single molecule mechanics - towards high throughput BCMP Trainee Committee Apr 16, 2015 Gary Ruvkun, PhD C. elegans surveillance of core cellular components to detect and defend pathogen attacks, real or imagined Junying Yuan (Cell Bio) Apr 23, 2015 Seth Darst, PhD Structural studies of bacterial transcription Sun Hur (BCMP) Apr 30, 2015 Edith Heard, PhD Epigenetic mechanisms in development and disease: Lessons from the inactive X chromosome Danesh Moazed (Cell Bio) May 7, 2015 Wei Yang, PhD Chemistry of DNA transactions Joseph Loparo (BCMP) May 14, 2015 Jennifer A Doudna, PhD The world of CRISPRs: From biology to breakthrough technology Tom Rapoport (Cell Bio) May 28, 2015 Bruce Beutler, MD Forward genetic analysis of mammalian immunity in real time Tom Rapoport (Cell Bio) -
2013-2014
DATE SPEAKER TITLE HOST (Dept) Sep 12, 2013 Ramanujan Hegde, FRS Membrane protein biogenesis and quality control Tom Rapoport (Cell Bio) Sep 19, 2013 Xi He, Ph.D. Understanding Wnt signaling in development and disease Andrew Lassar (BCMP) Oct 3, 2013 Adam Cohen, Ph.D. Bringing bioelectric phenomena to light Joseph Loparo (BCMP) Oct 24, 2013 Leemor Joshua-Tor, Ph.D. Slicer and the Argonautes Danesh Moazed (Cell Bio) Oct 31, 2013 Michael Green, Ph.D. Tumor Suppressor Genes: Mechanisms of Inactivation, Discovery and Therapeutic Potential Kevin Struhl (BCMP) Nov 7, 2013 Diane Mathis, Ph.D. T cell control of organismal metabolism Bruce Spiegelman (Cell Bio) Nov 14, 2013 Phil Cole, M.D., Ph.D. Chemical Approaches to Understanding and Modulating Cell Signaling Stephen Blacklow (BCMP) Nov 21, 2013 Mike Levine, Ph.D. Mechanisms of transcriptional precision in the Drosophila embryo Davie Van Vactor (Cell Bio) Dec 5, 2013 Samie Jaffrey, Ph.D. Imaging RNA and RNA biology using RNA mimics of green fluorescent protein John Flanagan (Cell Bio) Dec 12, 2013 Susan Lindquist, Ph.D. Yeast to human IPS cell discovery platform for protein folding diseases Sun Hur (BCMP) Jan 9, 2014 Christopher Hill, Ph.D. Proteasome Associations Stephen Blacklow (BCMP) Jan 16, 2014 Sangeeta Bhatia, M.D., Ph.D. Building Hepatic Tissues for Disease Modeling and Therapy Cell Bio Graduate Students Jan 23, 2014 Daniel Durocher, Ph.D. Cell cycle regulation of DNA double - strand break repair Johannes Walter (BCMP) Feb 6, 2014 Judy Lieberman, M.D., Ph.D. Bug Exterminators: A New Immune Defense Against Bacteria Timothy Springer (BCMP) Feb 20, 2014 Jonathon Howard, Ph.D. Ciliary and flagellar motility: From single molecules to collective motion David Pellman (Cell Bio) Mar 6, 2014 Shelley Berger, Ph.D. Epigenetic regulation of aging and senescence: and its not all bad news! Richard Gregory (BCMP) Mar 13, 2014 Ron Breaker, Ph.D. Riboswitches, Ribozymes, and the Ancient RNA World Danesh Moazed (Cell Bio) Mar 20, 2014 Eduardo Perozo, Ph.D. Structural Basis of Voltage-Dependent Gating in Ion Channels and Enzymes James Chou (BCMP) Mar 27, 2014 Steve Jacobsen, Ph.D. Genetics and genomics of gene silencing Yang Shi (Cell Bio) Apr 3, 2014 Yi Zhang, Ph.D. Mechanism and function of dynamic regulation of DNA methylation by TET and TDG proteins Stephen Buratowski (BCMP) Apr 10, 2014 Sandra Schmid, Ph.D Star-Gazing: Insights into the regulation of clathrin-mediated endocytosis from quantitative live cell imaging Tom Kirchhausen (Cell Bio) Apr 17, 2014 Robert Roeder, Ph.D. Transcriptional Regulatory Mechanisms in Animal Cells Kevin Struhl (BCMP) Apr 24, 2014 Daniel Louvard, Ph.D. Plasticity and repair of intestinal mucosa is mediated by actin microfilaments Spyros Artavanis-Tsakonas (Cell Bio) May 1, 2014 Doug Melton, Ph.D. Making Pancreatic Beta Cells George Daley (BCMP) May 8, 2014 Dan Gottschling, Ph.D. Organelle deterioration with age: The limits of an interconnected cellular system Dan Finley (Cell Bio) May 15, 2014 John Kuriyan, Ph.D. Structural Mechanisms in CAMK-II Regulation Stephen Harrison (BCMP) May 21, 2014 David Agard, Ph.D. Structural mechanisms of microtubule nucleation and prokaryotic tubulin polymerization Samara Reck-Peterson (Cell Bio) May 29, 2014 Joan Steitz, Ph.D. Noncoding RNAs: with a Viral Twist Stephen Buratowski (BCMP) Jun 5, 2014 Peter Walter, Ph.D. Unfolded Protein Response in Health and Disease Tom Rapoport (Cell Bio) Jun 12, 2014 Jim Wells, Ph.D. New Engineered Tools for Signaling Stephen Blacklow (BCMP) -
2012-2013
DATE SPEAKER TITLE HOST (Dept) Jan 10, 2013 Rachel Green, Ph.D. Kevin Struhl (BCMP) Jan 17, 2013 Scott Sternson, Ph.D. Stephen Liberles (Cell Bio) Jan 31, 2013 Kathryn Anderson, Ph.D. Cilia, centrosomes and signaling in the mouse embryo Adrian Salic (Cell Bio) Feb 7, 2013 Jue Chen, Ph.D. James Chou (BCMP) Feb 21, 2013 Walter Chazin, Ph.D. Y. Dimitrova (BCMP) Feb 28, 2013 Amita Sehgal, Ph.D. Genetic Basis of Sleep, Wake Cycles, Control of Timing and the Need to Sleep Cell Biology Graduate Students Mar 14, 2013 Joe DiRisi, Ph.D. Strange Tails in Viral Discovery Tom Rapoport (Cell Bio) Mar 18, 2013 Patrick Cramer, Ph.D. Gene Transcription: From Molecular Movies to Regulatory Systems Stephen Buratowski (BCMP) Mar 28, 2013 Maria Carmo-Fonseca, M.D., Ph.D. Fidelity of Gene Expression Tom Kirchhausen (Cell Bio) Apr 4, 2013 Bob Weinberg, Ph.D. Steve Harrison (BCMP) Apr 11, 2013 Thomas Tuschl, Ph.D. Characterization of Human Regulatory RNAs & RNA-Binding Proteins Danesh Moazed (Cell Bio) Apr 25, 2013 Tarun Kapoor, Ph.D. Examining Mechanisms Underlying the Self- Organized Assembly of the Cell Division Apparatus Samara Reck-Peterson (Cell Bio) May 2, 2013 Jennifer Doudna, Ph.D. RNA-mediated genome defense in bacteria Sun Hur (BCMP) May 16, 2013 Chris Burge, Ph.D. Diverse Functions of Splicing Factors & Alternative mRNA Isoforms Richard Gregory (BCMP) May 30, 2013 Steven Bell, Ph.D. Initiation of Eukaryotic DNA Replication BCMP Trainee Committee