Stephen Liberles

Stephen Liberles, Ph.D.

Professor of Cell Biology, Harvard Medical School
Tutor in Molecular and Cellular Biology, Faculty of Arts & Sciences

Stephen Liberles, Ph.D. is a Professor and HHMI Investigator in the Cell Biology Department at Harvard Medical School. Dr. Liberles received an undergraduate degree in Chemistry from Harvard in 1994, and a Ph.D. in Chemistry and Chemical Biology from Harvard in 1999, working in the lab of Stuart Schreiber. He then performed post-doctoral work in the lab of Linda Buck, first at Harvard Medical School and then at the Fred Hutchinson Cancer Research Center in Seattle.

The Liberles Lab focuses on the molecular neuroscience of sensory systems, including olfaction, pheromone sensing, taste, and internal organ senses of the vagus nerve. Some discoveries from his lab include characterizing non-classical families of olfactory receptors, odors and pheromones that stimulate innate behaviors, vagus nerve cell types that selectively control autonomic physiology, and mechanisms underlying sensation within internal organs, including airway stretch and changes in aortic blood pressure.

Harvard Medical School

Dept. of Cell Biology, LHRRB 601A

240 Longwood Avenue

Boston, MA 02115

Lab phone: 617-432-7283

Lab fax: 617-432-7285

Control of feeding by Piezo-mediated gut mechanosensation in Drosophila.
Authors: Authors: Min S, Oh Y, Verma P, Whitehead SC, Yapici N, Van Vactor D, Suh GS, Liberles S.
Elife
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Area Postrema Cell Types that Mediate Nausea-Associated Behaviors.
Authors: Authors: Zhang C, Kaye JA, Cai Z, Wang Y, Prescott SL, Liberles SD.
Neuron
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An Airway Protection Program Revealed by Sweeping Genetic Control of Vagal Afferents.
Authors: Authors: Prescott SL, Umans BD, Williams EK, Brust RD, Liberles SD.
Cell
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Arterial Baroreceptors Sense Blood Pressure through Decorated Aortic Claws.
Authors: Authors: Min S, Chang RB, Prescott SL, Beeler B, Joshi NR, Strochlic DE, Liberles SD.
Cell Rep
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Defined Paraventricular Hypothalamic Populations Exhibit Differential Responses to Food Contingent on Caloric State.
Authors: Authors: Li C, Navarrete J, Liang-Guallpa J, Lu C, Funderburk SC, Chang RB, Liberles SD, Olson DP, Krashes MJ.
Cell Metab
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Neural Sensing of Organ Volume.
Authors: Authors: Umans BD, Liberles SD.
Trends Neurosci
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Sexual rejection via a vomeronasal receptor-triggered limbic circuit.
Authors: Authors: Osakada T, Ishii KK, Mori H, Eguchi R, Ferrero DM, Yoshihara Y, Liberles SD, Miyamichi K, Touhara K.
Nat Commun
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PIEZOs mediate neuronal sensing of blood pressure and the baroreceptor reflex.
Authors: Authors: Zeng WZ, Marshall KL, Min S, Daou I, Chapleau MW, Abboud FM, Liberles SD, Patapoutian A.
Science
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Author Correction: Nociceptor sensory neurons suppress neutrophil and ?d T cell responses in bacterial lung infections and lethal pneumonia.
Authors: Authors: Baral P, Umans BD, Li L, Wallrapp A, Bist M, Kirschbaum T, Wei Y, Zhou Y, Kuchroo VK, Burkett PR, Yipp BG, Liberles SD, Chiu IM.
Nat Med
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Liraglutide Modulates Appetite and Body Weight Through Glucagon-Like Peptide 1 Receptor-Expressing Glutamatergic Neurons.
Authors: Authors: Adams JM, Pei H, Sandoval DA, Seeley RJ, Chang RB, Liberles SD, Olson DP.
Diabetes
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