Spyros Artavanis-Tsakonas

Spyros Artavanis-Tsakonas, Ph.D.

Professor of Cell Biology, Emeritus (HMS)
Professeur au Collège de France

Spyros Artavanis-Tsakonas, Ph.D., is Professor Emeritus of Cell Biology but continues to maintain a research group. He received his doctoral degree at Cambridge University, England and pursued postdoctoral research at the University of Basel, Switzerland, and Stanford University. He has been a faculty member at Harvard Medical School's Cell Biology department since 1998, and was Chief Scientific Officer at Biogen from 2012 until 2016.

Using molecular and genetic approaches, the Artavanis-Tsakonas lab is examining how various signals are integrated in undifferentiated cells in order to dictate cell fates. Our main experimental system is Drosophila and are interested in exploiting this system as a tool to explore human biology and understand the underlying mechanisms of pathologies with the current focus on neurodegeneration.

Harvard Medical School

Dept. of Cell Biology, LHRRB 301C

240 Longwood Avenue

Boston, MA 02115

Lab phone: 617-432-7107

Journal of Experimental Zoology
Authors: Authors: Genetic and developmental analysis of the facet alleles in the Notch locus
1990; 27:23-27.
1997.
Authors: Authors: Manipulation of Non-Terminally Differentiated Cells Using the Notch Pathway

1992.
Authors: Authors: Human Notch and Delta, Binding Domains in Toporythmic Proteins, and Methods Based Thereon

Manipulation of Non-Terminally Differentiated Cells Using the Notch Pathway
Authors: Authors: Artavanis-Tsakonas et al
1998.
Manipulation of Tissue or Organ Type Using the Notch Pathway
Authors: Authors: Artavanis-Tsakonas et al
2001.
1997.
Authors: Authors: Nucleotide and Protein Sequences on the Vertebrate Delta Genes and Methods Based Thereon

Development
Authors: Authors: The Involvement of Deltex in Notch Signaling
1995; 121:2633-44.
Delta Cleavage Products and Methods Based Thereon
Authors: Authors: Artavanis-Tsakonas et al
2000.
Delta Fragments and Derivatives and Methods Based Thereon
Authors: Authors: Artavanis-Tsakonas
1998.