Spyros Artavanis-Tsakonas

Spyros Artavanis-Tsakonas, Ph.D.

Professor of Cell Biology, Emeritus (HMS)
Professeur au Collège de France

Spyros Artavanis-Tsakonas, Ph.D., is Professor Emeritus of Cell Biology but continues to maintain a research group. He received his doctoral degree at Cambridge University, England and pursued postdoctoral research at the University of Basel, Switzerland, and Stanford University. He has been a faculty member at Harvard Medical School's Cell Biology department since 1998, and was Chief Scientific Officer at Biogen from 2012 until 2016.

Using molecular and genetic approaches, the Artavanis-Tsakonas lab is examining how various signals are integrated in undifferentiated cells in order to dictate cell fates. Our main experimental system is Drosophila and are interested in exploiting this system as a tool to explore human biology and understand the underlying mechanisms of pathologies with the current focus on neurodegeneration.

Harvard Medical School

Dept. of Cell Biology, LHRRB 301C

240 Longwood Avenue

Boston, MA 02115

Lab phone: 617-432-7107

Primary structure of triosephosphate isomerase from Bacillus stearothermophilus.
Authors: Authors: Artavanis-Tsakonas S, Harris JI.
Eur J Biochem
View full abstract on Pubmed
Genetic and molecular analysis of the 87A7 and 87C1 heat-inducible loci of D. melanogaster.
Authors: Authors: Ish-Horowicz D, Pinchin SM, Schedl P, Artavanis-Tsakonas S, Mirault ME.
Cell
View full abstract on Pubmed
Organization of the multiple genes for the 70,000-dalton heat-shock protein in Drosophila melanogaster.
Authors: Authors: Mirault ME, Goldschmidt-Clermont M, Artavanis-Tsakonas S, Schedl P.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Physical map of two D. melanogaster DNA segments containing sequences coding for the 70,000 dalton heat shock protein.
Authors: Authors: Moran L, Mirault ME, Tissières A, Lis J, Schedl P, Artavanis-Tsakonas S, Gehring WJ.
Cell
View full abstract on Pubmed
Genes for the 70,000 dalton heat shock protein in two cloned D. melanogaster DNA segments.
Authors: Authors: Artavanis-Tsakonas S, Schedl P, Mirault ME, Moran L, Lis J.
Cell
View full abstract on Pubmed
Two hybrid plasmids with D. melanogaster DNA sequences complementary to mRNA coding for the major heat shock protein.
Authors: Authors: Schedl P, Artavanis-Tsakonas S, Steward R, Gehring WJ, Mirault ME, Goldschmidt-Clermont M, Moran L, Tissières A.
Cell
View full abstract on Pubmed
Purification of a protein from unfertilized eggs of Drosophila with specific affinity for a defined DNA sequence and the cloning of this DNA sequence in bacterial plasmids.
Authors: Authors: Weideli H, Schedl P, Artavanis-Tsakonas S, Steward R, Yuan R, Gehring WJ.
Cold Spring Harb Symp Quant Biol
View full abstract on Pubmed
The 5S genes of Drosophila melanogaster.
Authors: Authors: Artavanis-Tsakonas S, Schedl P, Tschudi C, Pirrotta V, Steward R, Gehring WJ.
Cell
View full abstract on Pubmed
Diplomarbeit bei Prof Dr.V
Authors: Authors: Synthese von Peptidsubstraten fuer alpha Chymotrypsin
Prelog
Modulation of Notch signals elicit signature tumors and inhibit ras induced oncogenesis in the mouse mammary epithelium
Authors: Authors: Kiaris, H., Grimm, L., Politi, K., Fisher, P., Efstratiadis, A., and Artavanis-Tsakonas, S.,
(Submitted)