Adrian Salic

Adrian Salic, Ph.D.

Professor of Cell Biology (HMS)
LHRRB 401A
617-432-6341
Salic Lab

Adrian Salic, Ph.D. was appointed Assistant Professor of Cell Biology in 2005, after completing his postdoctoral research in the Department of Systems Biology at Harvard Medical School. He received his PhD from Harvard University in 2000. His development of novel tools to detect DNA and RNA synthesis resulted in the creation of the commerically-available "Click-iT" EdU and EU kits that are now widely used by labs around the world.

The Salic lab studies biochemical and cellular mechanisms involved in signal transduction through the Hedgehog signaling pathway. We also develop and apply new chemical technologies to study the cell biology of lipids.

Harvard Medical School

Dept. of Cell Biology, LHRRB 401A

240 Longwood Avenue

Boston, MA 02115

Lab phone: 617-432-6341

Lab fax: 617-432-1190

Distinct Cation Gradients Power Cholesterol Transport at Different Key Points in the Hedgehog Signaling Pathway.
Authors: Authors: Petrov K, Wierbowski BM, Liu J, Salic A.
Dev Cell
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Structural Basis of Smoothened Activation in Hedgehog Signaling.
Authors: Authors: Huang P, Zheng S, Wierbowski BM, Kim Y, Nedelcu D, Aravena L, Liu J, Kruse AC, Salic A.
Cell
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Structural Basis of Smoothened Activation in Hedgehog Signaling.
Authors: Authors: Huang P, Zheng S, Wierbowski BM, Kim Y, Nedelcu D, Aravena L, Liu J, Kruse AC, Salic A.
Cell
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Sending and Receiving Hedgehog Signals.
Authors: Authors: Petrov K, Wierbowski BM, Salic A.
Annu Rev Cell Dev Biol
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Mechanism of inhibition of the tumor suppressor Patched by Sonic Hedgehog.
Authors: Authors: Tukachinsky H, Petrov K, Watanabe M, Salic A.
Proc Natl Acad Sci U S A
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Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling.
Authors: Authors: Huang P, Nedelcu D, Watanabe M, Jao C, Kim Y, Liu J, Salic A.
Cell
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Identification of a Paralog-Specific Notch1 Intracellular Domain Degron.
Authors: Authors: Broadus MR, Chen TW, Neitzel LR, Ng VH, Jodoin JN, Lee LA, Salic A, Robbins DJ, Capobianco AJ, Patton JG, Huppert SS, Lee E.
Cell Rep
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DyNAvectors: dynamic constitutional vectors for adaptive DNA transfection.
Authors: Authors: Clima L, Peptanariu D, Pinteala M, Salic A, Barboiu M.
Chem Commun (Camb)
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Dynamic constitutional frameworks (DCFs) as nanovectors for cellular delivery of DNA.
Authors: Authors: Turin-Moleavin IA, Doroftei F, Coroaba A, Peptanariu D, Pinteala M, Salic A, Barboiu M.
Org Biomol Chem
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Bioorthogonal probes for imaging sterols in cells.
Authors: Authors: Jao CY, Nedelcu D, Lopez LV, Samarakoon TN, Welti R, Salic A.
Chembiochem
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