2023-2024
|
2022-2023
DATE | SPEAKER | LAB | TALK TITLE |
Sep 7, 2022 | Mahtab Dastpak | Reed | Role of the Essential Splicing Factor SF3B1 in Normal and Neoplastic Hematopoieses |
Sep 14, 2022 | Conor Ronayne | Puigserver | Mitochondrial Ribosome Signaling and Survival Mechanisms in Mitochondrial Disease |
Sep 28, 2022 | Anand Saminathan | Kirchhausen | How Antisense Oligonucleotides Enter Cells |
Oct 5, 2022 | Conghui Yao | Haigis | Untargeted Metabolomics Reveals Novel Metabolic Markers for T Cell Activation |
Oct 26, 2022 | Yuan Gao | Rapoport | Protein Import into Peroxisomes Occurs Through a Nuclear Pore-like Phase |
Nov 2, 2022 | Kevin Dong | Gygi | Phenotypic Screening with Cysteine-targeting Electrophiles to Discover Proteasome |
Nov 16, 2022 | Narek Darabedian | Chouchani | Development of a First in Class Inhibitor of Creatine Kinases |
Nov 30, 2022 | Sam Sedor | Shao | Quality Control of Orphan Ribosomal Subunit Proteins |
Dec 7, 2022 | Mu A | Spiegelman | Irisin Acts Through its Integrin Receptor in a Novel Two-Step Process |
Dec 14, 2022 | Anan Chen | Salic | Exploring the Roles of Double-Membrane Vesicles (DMVs) During Coronavirus Infection |
Jan 18, 2023 | Jon Markert | Farnung | Characterizing H3K36me3 deposition during transcription elongation |
Jan 25, 2023 | Pruthvi Gowda | Danial | Remodeling lipid metabolism for therapeutic differentiation of oncohistone gliomas |
Feb. 15, 2023 | Stamatis Papathanasiou | Pellman | Mitotic Errors as a novel source of Epigenetic Instability |
Feb 22, 2023 | Kelsey Hickey | Harper | Quantitative Mapping of the Autophagic Cargo during Nutrient Stress Reveals Membrane Receptors for Golgiphagy |
Mar 1, 2023 | Ngan Phan | Lee | Mechanism of translation repression mediated by elF3 |
Mar 15, 2023 | Mike Schappe | Liberles | Neural-epithelial coding of airway senses |
Mar 29, 2023 | Yann Cormerais | Manning | Defining in vivo the role of PI3K-mTORC1 signaling in the regulation of systemic glucose metabolism |
Apr 5, 2023 | Alba Rodriguez Meira | Bernstein | Developing a molecular toolkit to study epigenetic evolution in cancer |
Apr 12, 2023 | Stefan Niekamp | Subramanian | Polycomb repressive complex 1 composition and nucleosomal scaffold properties determine extend of chromatin condensation |
Apr 26, 2023 | Valentina Rossio | King | Discovery of new deubiquitylating enzyme substrates in Xenopus egg extract |
May 3, 2023 | Jared Johnson | Cantley | Intrinsic substrate specificity of the human protein tyrosine kinome |
May 10, 2023 | Deyang Yu | Puigserver | Lysosomal cyst(e)ine regulates melanoma, melanoma dedifferentiation, and ferroptsosis sensitivity |
May 17, 2023 | Juntao Yu | Moazed | DNA replication-coupled parental histone transfer and epigenetic inheritance |
June 7, 2023 | Kumar Aavula | Van Vactor | miRNA mediated regulation of activity induced synaptic plasticity |
June 14, 2023 | Jennifer Waters, Tally Lambert, Federico Gasparoli | NIC | Online tools for learning and performing light microscopy |
2021-2022
DATE | SPEAKER | LAB | TALK TITLE |
Sep 15, 2021 | Zhejian Ji | Rapoport Lab | Translocation of polyubiquitinated protein substrates by the hexameric Cdc48 ATPase |
Sep 22, 2021 | Jiaxin Liang | Puigserver Lab | Endosome Trafficking Defines Mevalonate Pathway Sensitivity in Tumor Resistance |
Sep 29, 2021 | Leila Revollo | Whitman Lab | Establishing functions for the secreted tyrosine kinase VLK |
Oct 20, 2021 | Jiaming Li | Gygi Lab | Proteome-wide mapping of short-lived proteins in human cells |
Nov 17, 2021 | Haopeng Xiao | Chouchani Lab | Architecture of the outbred brown fat proteome defines regulators of metabolic physiology |
Dec 15, 2021 | Vincent Chu | Shao Lab | Selective destabilization of polypeptides synthesized from NMD-targeted transcripts |
Jan 5, 2022 | Kumar Aavula | Van Vactor Lab | miRNA mediated regulation of activity induced synaptic plasticity |
Jan 12, 2022 | Bryan Seguinot | Finley Lab | TBCEL-mediated degradation of tubulin during red blood cell differentiation |
Jan 19, 2022 | Melanie Mittenbuhler | Spiegelman Lab | Isolation of interstitial fluids reveals novel secreted bioactive proteins from muscle and fat tissues |
Feb 9, 2022 | Giuseppe Di Caprio | Kirchhausen Lab | Deep neural network training for automated identification of intracellular substructures in volumetric electron microscopy |
Feb 16, 2022 | Gengjing Zhao | Pellman Lab | The Mitotic Actin Cytoskeleton and Endoplasmic Reticulum Morphology Control the Pattern of Nuclear Envelope Assembly |
Feb 23, 2022 | Judy Shen | Sander Lab | Study of combination therapy in ovarian cancer using mass-spectrometry based proteomics |
Mar 9, 2022 | Donghoon Lee | Goldberg Lab | Molecular mechanisms for activation of 26S proteasome and p97 by ZFAND5 |
Mar 16, 2022 | Shaoni Mukhopadhyay | Lee Lab | Regulation of the Epitranscriptome via eIF3d during the Integrated Stress Response (ISR) |
Mar 30, 2022 | Henning Arlt | Farese/Walther Lab | Mechanistic insight into lipid droplet biogenesis |
Apr 6, 2022 | Melissa Hoyer | Harper Lab | Organelle quality control in neuronal cells |
Apr 13, 2022 | Aaron Hosios | Manning Lab | mTORC1 regulates a lysosome-dependent adaptive shift in intracellular lipid species |
Apr 20, 2022 | Xiangkun Han | Brugge Lab | NRF2, the master regulator of more than anti-oxidative stress |
Apr 27, 2022 | Accalia Fu | Danial Lab | Glucose fuels choice metabolic paths for pancreatic b-cell survival in inflammation |
May 11, 2022 | Haining Zhou | Moazed Lab | Nascent RNA Degradation on Chromatin Contributes to Gene Repression |
May 18, 2022 | Farah Haque | Subramanian Lab | Cytoskeletal regulation of a transcription factor by DNA mimicry |
May 25, 2022 | Chen Ran | Liberles Lab | Optical deciphering of internal sensory codes in the brain |
Jun 1, 2022 | Peiqing Feng | Rapoport Lab | The tale of three RINGS: a heterotrimeric ubiquitin ligase complex forms the peroxisomal retro-translocon |
Jun 8, 2022 | Tomer M. yaron | Cantley Lab | The Kinase Library: A Global Atlas of the Human Protein Kinome |
2020-2021
DATE | SPEAKER | LAB | TALK TITLE |
Sep 16, 2020 | Pushpa Sharma | Van Vactor Lab | microRNA, miR-1000 mediated control of metabolism via a novel neuropeptide |
Sep 23, 2020 | Phillip Dumesic | Spiegelman Lab | Translational regulation of PGC1α and oxidative metabolism |
Sep 30, 2020 | Heng Zhao | Yuan Lab | Modulating TRADD to restore cellular homeostasis and inhibit apoptosis |
Oct 7, 2020 | Xudong Wu | Rapoport Lab | Mechanism of ERAD-L mediated by the Hrd1 complex |
Oct 21, 2020 | Dylan Mitchell | Gygi Lab | A Proteome-Wide Map of Drug Mechanism of Action |
Oct 28, 2020 | Mike McKenna | Shao Lab | The P5A-ATPase is a transmembrane helix dislocase |
Nov 18, 2020 | Sharon Hung | Finley Lab | Modulation of cholesterol metabolism by UBE3B |
Dec 9, 2020 | Navdar Sever | Rapoport Lab | Mechanism of lamellar body formation by lung surfactant protein B |
Dec 16, 2020 | Brad Wierbowski | Salic Lab | A Molecular Relay for Sending and Receiving Hedgehog Signals (Dissertation in 25 Min) |
Jan 13, 2021 | Ilaria Elia | Haigis Lab | Modulating pyruvate fate improves metabolic fitness of CD8+ T cells in tumors |
Jan 20, 2021 | Pedro Latorre-Muro | Puigserver Lab | A cold-inducible PERK/OGT axis controls TOM70-assisted protein import and cristae formation |
Jan 27, 2021 | Ben Fram | Sander Lab | Generating Sequence-divergent Proteins Using an Evolution-based Model of Protein Function |
Feb 17, 2021 | Dong Wook Choi | Danial Lab | Metabolic Fuel Preference and the Excitable Brain |
Mar 10, 2021 | Kenneth Gray | Brugge Lab | The Protean Lives and Times of the Alveolar Progenitor |
Mar 17, 2021 | Galen Collins | Goldberg Lab | The Shuttling Factor & Protease Ddi2 Regulates Protein Degradation and Antigen Presentation |
Mar 31, 2021 | Anita Reddy | Chouchani Lab | Examining the Role of Succinate Signaling in Muscle Remodeling Following Exercise |
Apr 7, 2021 | Mitchell Leibowitz | Pellman Lab | Chromothripsis as an on-target consequence of genome editing |
Apr 14, 2021 | Francois Thelot | Liao Lab | Working harder, not smarter: wasteful ATP hydrolysis by the lipopolysaccharide floppase MsbA |
Apr 21, 2021 | Jianhua Shi | Flanagan Lab | Tau is a novel substrate for Protein Tyrosine Phosphatase σ(PTPσ) -participating in PTPσ mediated neurodevelopment, neural injury and degeneration |
Apr 28, 2021 | Anwesha Sanyal | Kirchhausen Lab | Inhibition of PIKfyve kinase prevents alpha-synuclein aggregation and averts neuronal cell death |
May 12, 2021 | Marito Hayashi | Liberles Lab | Gut-brain communication mechanisms underlying feeding control |
May 19, 2021 | Tiasha Shafiq | Moazed Lab | DNA-Sequence Dependent Epigenetic Inheritance in Mammalian Cells |
May 26, 2021 | Hankum Park | Harper Lab | Quantitative proteomics for endo-lysosomal amyloid processing in Alzheimer's disease |
Jun 2, 2021 | Aditi Jatkar | Farese/Walther Lab | Mechanism underlying the regulation of SREBP-1 activation by glycerolipids |
2019-2020
DATE | SPEAKER | LAB | TALK TITLE |
Sep 11, 2019 | Eduardo Balsa Martinez | Puigserver Lab | Defective NADPH Production in Mitochondrial Disease Complex I Causes Inflammation and Cell Death |
Sep 18, 2019 | Marie Bao | Departments of Cell Biology and BCMP | Tips on Getting Published: Insights into the Editorial Process |
Oct 9, 2019 | Marcelo Cicconet | IDAC | Mobile, cloud, assistants, machine learning: analyzing images like it's 2019 |
Oct 23, 2019 | Jiuchun Zhang | Initiative | CRISPR Services at the Cell Biology Initiative |
Oct 30, 2019 | Mohan Chitraju | Farese/Walther Lab | Life without fat: insights into energy balance from a novel murine model |
Nov 13, 2019 | Jeeyun Chung | Farese/Walther Lab | the protein machinery of lipid droplet formation |
Nov 20, 2019 | Maria Del Carmen Fernandez-Aguera Rodriguez | Danial Lab | Metabolic Fuel Preference and the Excitable Brain |
Dec 4, 2019 | Reza Behrouzi | Moazed Lab | what we talk about when we talk about heterochromatin |
Dec 18, 2019 | Erdem Sendinc | Shi Lab | Regulation of gene expression through RNA modifications |
Jan 15, 2020 | Yaara Oren | Brugge Lab | Using Watermelons to uncover metabolic adaptations of cancer persister cells |
Jan 22, 2020 | Yizhi Sun | Spiegelman Lab | Futile Creatine Cycle: Novel Pathway of Thermogenesis |
Jan 29, 2020 | Masanori Naito | Yuan Lab | Apoptosis and necroptosis in a disease model |
Feb 5, 2020 | Alban Ordureau | Harper Lab | Molecular Roadmap to PINK1/Parkin Mitophagy Signaling |
Feb 19, 2020 | Valentina Rossio | King Lab | Unmasking functional redundancy of deubiquitylases reveals a prominent role of USP7 in rescuing proteins from degradation |
Feb 26, 2020 | David Nusinow | Gygi Lab | Quantitative Proteomics of the Cancer Cell Line Encyclopedia |
Mar 4, 2020 | Xuewu Sui | Liao Lab | Structure and catalytic mechanism of a human triacylglycerol synthesis enzyme |
Apr 8, 2020 | GaYoung Lee | Liberles Lab | Not all those who wander are lost: Mechanisms underlying organ-specific targeting by the vagus nerve |
Apr 15, 2020 | Alexandra Franz | Sander Lab | Building signaling network models using mass spectrometry-based proteomics |
Apr 22, 2020 | Jefte Drijvers | Haigis Lab | Metabolic screening identifies ferroptosis as a vulnerability of CD8+ T cells |
Apr 29, 2020 | Neil Umbreit | Pellman Lab | Mechanisms generating cancer genome complexity from a single cell division error |
May 13, 2020 | Haopeng Xiao | Chouchani Lab | A quantitative tissue-specific landscape of protein redox regulation during aging |
May 20, 2020 | Jordan Verplank | Goldberg Lab | Raising cGMP to activate the Ubiquitin Proteasome System and prevent proteotoxic diseases |
2018-2019
DATE | SPEAKER | LAB | TALK TITLE |
Sep 12, 2018 | Jim Gould | Harvard Medical School | Making the Most of Your Training Experience at HMS |
Sep 19, 2018 | Zhe Sha | Goldberg Lab | Inhibition of ubiquitination causes sumoylation of nuclear proteins |
Sep 26, 2018 | Valentina Rossio | King Lab | Proteomic analysis of deubiquitinating enzyme targets and specificity in Xenopus extract |
Oct 17, 2018 | Xing Zeng | Spiegelman Lab | Innervation of Thermogenic Adipose Tissue through a Clstn3β/S100b Axis |
Oct 24, 2018 | Ayaz Najafov | Yuan Lab | Escape from necroptosis in cancer |
Oct 31, 2018 | Xudong Wu | Rapoport Lab | Structural basis of ERAD mediated by the Hrd1 ubiquitin ligase complex |
Nov 14, 2018 | Chi Luo | Puigserver Lab | Multifaceted Roles of PGC1a in Melanoma Pathogenesis |
Nov 28, 2018 | Sharan Swarup | Harper Lab | The retromer complex regulates trafficking of lysosomal proteins |
Dec 12, 2018 | Talley Lambert | Nikon Imaging Center | FPbase.org: a community-editable fluorescent protein database and microscopy resource |
Dec 19, 2018 | Wanqiang Sheng | Shi Lab | Investigating the role of LSD1 in tumor immunity and immunotherapy |
Jan 9, 2019 | Jon Van Vranken | Gygi Lab | The role of mitochondrial fatty acid synthesis in supporting cellular respiration |
Jan 30, 2019 | Xuewu Sui | Farese/Walther Lab | Cryo-electron microscopy structure of the lipid droplet-formation protein seipin |
Feb 6, 2019 | Yanyan Li | Liao Lab | Structural Snapshots of Lipopolysaccharide Extraction from Bacterial Inner Membrane |
Feb 13, 2019 | Nao Horio | Liberles Lab | The olfactory circuit of aversive behavior in zebrafish |
Feb 20, 2019 | Dong Wook Choi | Danial Lab | Regulation of de novo lipogenesis through a glucose sensitive transcriptional complex |
Feb 27, 2019 | Gergana Shipkovenska | Moazed Lab | Epigenetic inheritance in the fission yeast |
Mar 6, 2019 | Ilja Kusters | Kirchhausen Lab | Reconstitution of clathrin coated pit budding probed by single molecule imaging |
Mar 20, 2019 | Suha Abu Amara | Brugge Lab | Transient commensalism drives metastasis in a model of ovarian clear cell carcinoma |
Mar 27, 2019 | Mike Stiffler | Sander Lab | Protein Structure from Laboratory Evolution |
Apr 3, 2019 | Alex Whiteley | Finley Lab | Using global proteomics of Ubqln2-mediated mouse models of ALS to reveal client proteins and potential pathways of disease development |
Apr 24, 2019 | Elma Zaganjor | Haigis Lab | The role of mitochondria in adipogenesis |
May 1, 2019 | I-Ju Lee | Pellman Lab | Nuclear Envelope Sealing: The ESCRT Machinery and More |
May 15, 2019 | Matthew Yip | Shao Lab | tRNA recycling and quality control from stalled ribosomes |
May 22, 2019 | Jianhua Shi | Flanagan Lab | HSPG inhibits scar formation and promotes axon regeneration and functional recovery after spinal cord injury |
Jun 5, 2019 | Evanna Mills | Chouchani Lab | Succinate accumulation controls activation of adipose tissue thermogenesis |
Jun 12, 2019 | Donghoon Lee | Goldberg Lab | ZFAND5 is a novel activator of proteasome and protein degradation |
Jun 19, 2019 | Brandon Woods | Van Vactor Lab | miRNA Control of Synaptic Morphogenesis |
Jun 26, 2019 | Ed Twomey | Rapoport Lab | Cryo-EM reveals mechanism of substrate processing by the Cdc48 ATPase complex |
2017-2018
DATE | SPEAKER | LAB | TALK TITLE |
Sep 13, 2017 | Amir Karger | Research Computing | HMS Research Computing: Helping CellBio Researchers Do Good (Fast!) Science on Computers |
Sep 20, 2017 | Niklas Mejhert | Farese/Walther Lab | Genetic determinants of lipid storage in macrophages |
Sep 27, 2017 | Sara Prescott | Liberles Lab | Building a 'Vagal Atlas': Clues to Internal Sensory Systems |
Oct 4, 2017 | Xinmin Li | Flanagan Lab | Axon Guidance at Intermediate Target Through Local Translation |
Oct 18, 2017 | Heeseon An | Harper Lab | Systematic Analysis of Ribophagy in Human Cells |
Oct 25, 2017 | Nobu Takahashi | Brugge Lab | Cancer Cells Co-opt the Neuronal Redox-Sensing Channel TRPA1 to Promote Oxidative Stress Tolerance |
Nov 8, 2017 | Hugo Santos | Van Vactor Lab | Untangled but still tied in knots: from SMA disease model transcriptomes to a SMN-specific gene regulatory network |
Nov 15, 2017 | Bradley Wierbowski | Salic Lab | How many factors does it take to move a Hedgehog: defining a necessary pathway upstream of ligand reception |
Nov 29, 2017 | Lin Deng | Pellman Lab | Premature mitotic entry induces genome instability by unloading DNA replicative helicase |
Dec 6, 2017 | Sejal Vyas | Haigis Lab | SIRT4 regulation of intestinal homeostasis in the DNA damage response |
Dec 13, 2017 | Gokul Upadhyayula | Kirchhausen Lab | Observing the Cell in Its Native State: Imaging Subcellular Dynamics in Multicellular Organisms |
Jan 3, 2018 | Huibing Wang | Yuan Lab | PELI1 functions as a dual modulator of necroptosis and apoptosis by regulating ubiquitination of RIPK1 and mRNA levels of c-FLIP |
Jan 10, 2018 | Nicholas Bodnar | Rapoport Lab | Structure of the Cdc48 ATPase with its cofactors Ufd1 and Npl4 |
Jan 24, 2018 | Seth Johnson | Van Vactor Lab | Determining the role of TACC in the development of the synapse in Drosophila |
Jan 31, 2018 | Hyeonwoo "Chad" Kim | Spiegelman Lab | Irisin Mediates Beneficial Exercise-induced Effects via Integrins |
Feb 7, 2018 | Eduardo Balsa | Puigserver Lab | ER and Nutrient Stress Promote Assembly of Respiratory Chain Supercomplexes Through PERK/eIF2α Axis |
Feb 14, 2018 | Alban Ordureau | Harper Lab | Spatial control of ubiquitin signals underlying mitophagy |
Feb 21, 2018 | Calie Fu | Danial Lab | Glucose-dependent partitioning of arginine to urea cycle protects beta cells from inflammation |
Feb 28, 2018 | Kevin Jiang | HMS Media Office | Science, News, and You |
Mar 14, 2018 | Michael Weber | Nikon Imaging Center | New possibilities for imaging your sample - microscope upgrades in the NIC |
Mar 21, 2018 | Jamie Anastas | Shi Lab | Targeting chromatin to induce differentiation in pediatric brain cancer |
Mar 28, 2018 | Mark Jedrychowski | Gygi Lab | Characterizing redox control of thermogenesis |
Apr 4, 2018 | Maja Edenius | Whitman Lab | Characterization of a Novel Mammalian Nutritional Stress Response Pathway |
Apr 11, 2018 | Ben Orlando | Liao Lab | Structure of the Mitochondrial Calcium Uniporter from Cryo-EM and X-ray Crystallography |
May 2, 2018 | Mark Currie | Moazed Lab | Clr4/Suv39h autoregulation prevents illegitimate heterochromatin formation |
May 9, 2018 | Josh Wilson-Grady | Finley Lab | The Biochemical Program of Extreme Terminal Differentiation |
May 16, 2018 | Alexandra Franz | Sander Lab | Systems Biology of Combination Therapy in Ovarian Cancer |
May 24, 2018 | Alison Ringel | Haigis Lab | Immunomodulatory mechanisms in the tumor microenvironment |
Jun 6, 2018 | Jordan VerPlank | Goldberg Lab | Raising cGMP enhances protein degradation and proteasome function |
Jun 13, 2018 | Alex Keszei | Shao Lab | Progress towards a structural view of protein triage |
2016-2017
DATE | SPEAKER | LAB | TALK TITLE |
Sep 21, 2016 | Yannis Zervantonakis | Brugge Lab | Systems analysis of signaling pathway adaption after PI3K-pathway inhibition to design effective ovarian cancer combination therapies |
Oct 5, 2016 | Kai Hu | Olsen Lab | VEGF-dependent Mechanisms in Bone Repair |
Oct 19, 2016 | Selwin Wu | Pellman Lab | Mechanisms linking centrosome amplification to the senescence associated secretory phenotype in cancer |
Oct 26, 2016 | Wei Mi | Liao Lab | cryoEM structures and mechanism of flippase in membrane |
Nov 30, 2016 | Yulu "Cherry" Liu | Salic Lab | Hedgehog Signaling in Ciliopathies |
Dec 7, 2016 | Brian Cunniff | Kirchhausen Lab | Mitochondrial positioning by Miro1 supports cell migration and clathrin mediated endocytosis |
Dec 14, 2016 | Yasushi Ito | Yuan Lab | RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS |
Jan 4, 2017 | Robert Powers | Rapoport Lab | Reconstitution of the tubular endoplasmic reticulum network with purified component |
Jan 11, 2017 | Pushpa Sharma, PhD | Van Vactor Lab | Role of microRNA, miR-980 in immune system of Drosophila melanogaster |
Jan 25, 2017 | Jessica Spinelli | Haigis Lab | Metabolic Recycling of Ammonia Facilitates Breast Cancer Growth and Proliferation |
Feb 1, 2017 | Danial Egan | Spiegelman Lab | Decoding PGC1a1 control of Energy Metabolism |
Feb 8, 2017 | Kfir Sharabi | Puigserver Lab | Small Molecule Screen Identifies Selective PGC-1α Gluconeogenic Inhibitors that Ameliorate Diabetic Symptoms |
Feb 22, 2017 | Jin-Mi Heo | Harper Lab | Spatio-temporal mapping of the PINK1-PARKIN mitophagy pathway |
Mar 1, 2017 | Sofia Ribeiro | Danial Lab | Metabolic control of neuronal activity by fuel substrate switching: A role for BAD |
Mar 15, 2017 | Talley Lambert | Nikon Imaging Center | Lattice Light Sheet Microscopy in the Cell Biology Microscopy Facility |
Mar 22, 2017 | Violetta Karwacki-Neisius | Shi Lab | Elucidating the role of the histone demethylase KDM5C in intellectual disability |
Mar 29, 2017 | Julian Mintseris | Gygi Lab | High Density Chemical Cross-linking for Modeling Protein Interactions |
Apr 5, 2017 | Yeonjin Kim | Whitman Lab | The Amino Acid Starvation Response Inhibits Inflammatory Diseases by a Novel Mechanism |
Apr 26, 2017 | Min Luo | Liao Lab | Invader capture in CRISPR - Viewing is believing! |
May 10, 2017 | Xiaoyi Wang | Moazed Lab | DNA sequence-dependent epigenetic inheritance of gene silencing and histone H3K9 methylation |
May 17, 2017 | Alexandra Greer | Finley Lab | Ubiquilin1 promotes stimulus-dependent proliferation by eliminating mislocalized mitochondrial proteins |
May 24, 2017 | Galen Collins | Goldberg Lab | Another Mechanism Regulating the 26S Proteasome: Ubiquitin Life (UbL) Domains Activate Multiple Steps in Conjugate Degradation |
May 31, 2017 | Benjamin Schubert | Sander Lab | Population-specific design of de-immunized protein biotherapeutics |
Jun 7, 2017 | Haejin Yoon | Haigis Lab | AMPK opposes PHD3 to promote fat oxidation through ACC2 |
Jun 14, 2017 | Binkai Chi | Reed Lab | Analysis of ALS-causative RNA binding proteins reveals that common factors are shared by motor neuron diseases |
2015-2016
DATE | SPEAKER | LAB | TALK TITLE |
Oct 7, 2015 | Kostadin Petrov | Salic Lab | The Mechanism of Patched Inhibition by Sonic Hedgehog |
Oct 21, 2015 | Kangmin He | Kirchhausen Lab | Direct probing of dynamic phosphoinositide switches during clathrin-mediated endocytosis |
Oct 28, 2015 | Neil Umbreit | Pellman Lab | A new model for chromosome bridge resolution based on nuclear envelope fragility and DNA damage |
Nov 18, 2015 | Su Chiang, Grant Zimmerman and Leandro Vetcher | Office of Technology Devlopment | The Blavatnik Biomedical Accelerator: Supporting Applied Life Sciences at Harvard |
Dec 2, 2015 | Isaac Harris | Brugge Lab | Looks can be deceiving: the roles of antioxidants in cancer |
Dec 16, 2015 | Julie Chen | Rapoport Lab | Mechanism of a cytosolic O-glycosyltransferase essential for the synthesis of a bacterial adhesion |
Jan 6, 2016 | Karina Gonzalez | Haigis Lab | Identifying metabolic vulnerabilities in tumors with low SIRT3 |
Jan 13, 2016 | Huajin Wang | Farese/Walther Lab | How Do Lipid Droplets Form From the Endoplasmic Reticulum? - Lessons From Studying The Lipodystrophy Protein Seipin |
Jan 27, 2016 | Ed Chouchani | Spiegelman Lab | Mitochondrial redox control of thermogenic adipose function |
Feb 3, 2016 | Israel Pichardo-Casas | Van Vactor Lab | Muscle maintenance and ALS: a common microRNA theme? |
Feb 10, 2016 | Joeva Barrow | Puigserver Lab | Bromodomain Inhibitors Correct Bioenergetic Deficiency Caused by Mitochondrial Disease Complex I Mutations |
Feb 24, 2016 | Talley Lambert | Nikon Imaging Center | Light sheet microscopy and other new resources in the Cell Biology Microscopy Facility |
Mar 2, 2016 | Long Li | Rapoport Lab | Crystal structure of a substrate-engaged SecY protein-translocation channel |
Mar 9, 2016 | Robert Liefke | Shi Lab | TBAGenome-wide modulation of transcription by the PRC2-associated factor C17orf96 |
Mar 23, 2016 | Liz Lane | Danial Lab | Glucose sensing and de novo lipogenesis |
Mar 30, 2016 | Laura Pontano-Vaites | Harper Lab | Mechanisms of selective autophagy and autophagosome maturation |
Apr 6, 2016 | Su Wu | Naar Lab | SREBP1-driven Lipogenesis Pathway in Melanoma |
Apr 13, 2016 | Qian Li | Liberles Lab | Non-canonical amine recognition evolved in a large clade of olfactory receptors |
Apr 20, 2016 | Leila Revollo | Whitman Lab | The role of VLK in the dynamics of extracellular matrix |
May 4, 2016 | Jiefei Geng | Yuan Lab | TAK1-mediated RIPK1 phosphorylation negatively regulates RIPK1-dependent apoptosis |
May 11, 2016 | Gloria Jih | Moazed Lab | RNAi@chromatin.pombe (Pizza Emoji) (Pizza Emoji) #H3K9methylation #genesilencing |
May 18, 2016 | Stefanie De Poot | Finley Lab | Unraveling the function of the proteasomal deubiquitinating enzyme UCH37 |
May 25, 2016 | Chueh-Ling Kuo | Goldberg Lab | Ubiquitin conjugates promote the association of Usp14 and Ube3c with proteasomes |
2014-2015
DATE | SPEAKER | LAB | TALK TITLE |
Sep 24, 2014 | Pengxiang Huang | Salic Lab | Activation of Hedgehog Signaling by Sterol-Triggered Conformational Switch in Smoothened |
Oct 1, 2014 | Frances Evesson | Kirchhausen Lab | Dysferlin to the rescue! Membrane repair in skeletal muscle cells |
Oct 8, 2014 | Hugo Arellano-Santoyo | Pellman Lab | Towards an understanding of the molecular mechanism of the unique biomechanical properties of the yeast kinesin-8 Kip3 |
Oct 22, 2014 | Shanye Yin | Reed Lab | Functional coupling of RNAP II transcription to pri-miRNA processing |
Oct 29, 2014 | Noga Ron-Harel | Haigis Lab | A Synchronized Program of Mitochondrial Remodeling and Fuel Metabolism Supports Naïve T cell Activation |
Nov 5, 2014 | Lisa Gallegos | Brugge Lab | |
Nov 12, 2014 | Fabian Romano-Chernac | Rapoport Lab | |
Nov 19, 2014 | Nora Kory | Farese & Walther Lab | |
Dec 3, 2014 | Romain Christiano | Farese & Walther Lab | |
Jan 21, 2015 | Kfir Sharabi | Puigserver Lab | |
Feb 4, 2015 | Lawrence Kazak | Spiegelman Lab | |
Feb 18, 2015 | Zhe Sha | Goldberg Lab | |
Feb 19, 2015 | Accalia Fu | Danial Lab | |
Mar 4, 2015 | Wei Huang | Olsen Lab | |
Mar 11, 2015 | Benoit Laurent | Shi Lab | |
Mar 18, 2015 | Xinmin Li | Flanagan Lab | |
Apr 8, 2015 | Christian Munch | Harper Lab | |
Apr 15, 2015 | Hongguang Xia | Yuan Lab | |
Apr 29, 2015 | Ryan Baldridge | Rapoport Lab | Exploring ERAD retro-translocation using a reconstituted system |
May 6, 2015 | Talley Lambert | Nikon Imaging Center | First impressions and optimization of 3D-structured illumination microscopy on the OMX Blaze |
May 13, 2015 | Rui Chang | Liberles Lab | Vagal sensory neuron subtypes that differentially control breathing |
May 27, 2015 | Miguel Prado | Finley Lab | Remodeling of the proteome by USP14 |
Jun 3, 2015 | Alexandre Wagschal | Naar Lab | Genome-wide identification of microRNAs regulating cholesterol/lipid homeostasis |
Jun 10, 2015 | Kaushik Ragunathan | Moazed Lab | How cells create and maintain memories of gene expression |
2013-2014
DATE | SPEAKER | LAB | TALK TITLE |
Sep 25, 2013 | Marcin Iwanicki | Brugge Lab | Targeting Mutant p53 and Cell-Cell Adhesion in Ovarian Cancer |
Oct 2, 2013 | Xiaoxiao Gu | Blenis Lab | Integration of mTOR and estrogen-ERK2 signaling in lymphangioleiomyomatosis (LAM) pathogenesis |
Oct 9, 2013 | W. Bret Redwine | Reck-Peterson Lab | The mystery of processivity: towards an understanding of the basis of motor properties in vivo |
Oct 30, 2013 | Jennifer Long | Van Vactor Lab | The role of microtubule dynamics during nervous system development |
Nov 6, 2013 | Ruby Yu | Moazed Lab | Identification of locus features that permit targeting by RNAi-mediated heterochromatin in fission yeast |
Nov 13, 2013 | Kwonmoo Lee | Danuser Lab | Mechanosensitivity in the Cooperative Dynamics of Actin Nucleators During Epithelial Cell Protrusion |
Dec 4, 2013 | Helin Norberg | Yuan Lab | Identification of a novel Degradation Pathway for Mutant p53 |
Dec 11, 2013 | Yong Yu | Reed Lab | U1 snRNP and FUS in coupling transcription to pre-mRNA splicing |
Jan 15, 2014 | Benedikt Bauer | Rapoport Lab | Elucidating the molecular mechanism of protein translocation by the SecA-ATPase |
Jan 29, 2014 | Nikolay Kukushkin | Goldberg Lab | Proteasome autoubiquitination regulates its function |
Feb 5, 2014 | Daniel Nedelcu | Salic Lab | Regulation of Smoothened in the Hedgehog Pathway |
Feb 12, 2014 | Seung Min Jeong | Haigis Lab | Regulation of metabolic response to DNA damage by SIRT4 |
Feb 26, 2014 | Michael Weekes | Gygi Lab | Quantitative Temporal Viromics: a new approach to investigate host-pathogen interaction |
Mar 5, 2014 | Yoonjin Lee | Puigserver Lab | Cyclin D1-CDK4 controls glucose metabolism independently of cell cycle progression |
Mar 12, 2014 | Maude Baldwin | Liberles Lab | Evolution of sweet taste perception in a nectar-feeding bird |
Mar 26, 2014 | Po-Lin Chiu | Walz Lab | Structural studies of lipid-protein interactions by using two-dimensional crystals of aquaporin-0 |
Apr 2, 2014 | Melissa Hancock | Flanagan Lab | Role of miRNA in axon development |
Apr 9, 2014 | Illana Stanley | Danial Lab | Metabolic Heterogeneity in Molecular Subsets of Diffuse Large B-Cell Lymphoma |
Apr 30, 2014 | Mijung Kwon | Pellman Lab | How cancer cells divide with too many centrosomes: the Achilles’ heel of cancer cells |
May 1, 2014 | Alex Stein | Rapoport Lab | |
May 7, 2014 | Anne White | Harper Lab | Quantitative analysis of the Hippo pathway in low and high-density cells |
May 14, 2014 | Andres Blanco | Shi Lab | RNAi screens for epigenetic regulators of differentiation in Acute Myeloid Leukemia |
2012-2013
DATE | SPEAKER | LAB | TALK TITLE |
Jan 9, 2013 | Alexis Lomakin | Danuser Lab | Myosin-II serves as global inhibitor of self-organizing polarity in immotile cells |
Feb 6, 2013 | Anthony Nguyen | Finley Lab | Ubiquitination in Erythropoiesis and the Pathophysiology of Anemias |
Feb 13, 2013 | Gaelle Laurent | Haigis Lab | SIRT4 controls the balance between lipid synthesis and catabolism by repressing malonyl-CoA Decarboxylase |
Feb 26, 2013 | Michael Weekes | Gygi Lab | |
Mar 6, 2013 | Rebecca Mathew | Moazed Lab | Storing memories: the role of miR-153 in long-term memory formation |
Mar 13, 2013 | Grant Zimmermann | Brugge Lab | |
Apr 10, 2013 | Neil Ganem | Pellman Lab | Tetraploidy, Aneuploidy,and Cancer |
Jun 5, 2013 | Dongyan Tan | Walz Lab | Structural and functional studies on the tethering complex TRAPPIII |
Jun 12, 2013 | Elizabeth McNeil | Van Vactor Lab | Tools to define microRNA regulatory complexity in Drosophila |