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2023-2024
DATE EVENT SPEAKER TALK TITLE Oct. 12, 2023 Cell Bio Seminar Paul Lehner, M.D., Ph.D., F.R.S. How immunosurveillance by HUSH protects your genome from the reverse flow of genetic information May 13, 2024 Cell Bio Seminar Manu Hegde, M.D., Ph.D. Factors and mechanisms for biogenesis of the membrane proteome May 29, 2024 Cell Bio Seminar Yoko Yazaki Sugiyama, Ph.D. Cortical Neural Circuits That Shape Memory Formation During Song Acquisition June 7, 2024 Cell Bio Seminar Elvan Böke, Ph.D. Evading ageing: Mitochondrial and proteostatic adaptations in oocytes June 7, 2024 Cell Bio Seminar Bernhard Lechtenberg, Ph.D. Branched ubiquitin chain formation
by the RBR E3 ubiquitin ligase RNF14
in ribosomal quality control -
2022-2023
DATE EVENT SPEAKER TALK TITLE Oct 24, 2022 Cell Bio Seminar Vaclav Veverka An interplay between order and disorder in proteins regulates transcription elongation March 7, 2023 Cell Bio Seminar Jorge Azevedo Dissecting the mechanism of protein import into peroxisomes using a mammalian cell-free in vitro system March 15, 2023 Cell Bio Seminar Olaf Stemmann Separase-mediated deacetylation of cohesin by HDAC8 facilitates sister chromatid separation April 12, 2023 Cell Bio Seminar Pedro Carvalho Quality control of membrane proteins at the endoplasmic reticulum June 8, 2023 Cell Bio Seminar Nikos Hatzakis A Quantum Leap of Understanding Protein Membrane Interactions by Single Particle Microscopy and Machine Learning June 16, 2023 Cell Bio Seminar Sung-Yon Kim Warm and full: neural circuits for behavioral regulation of homeostasis July 21, 2023 Cell Bio Seminar Noboru Mizushima Intracellular degradation by autophagy-dependent and independent pathways -
2021-2022
DATE EVENT SPEAKER TALK TITLE June 27, 2022 Cell Bio Seminar Harald Stenmark Membrane Dynamics and Cancer July 7, 2022 Cell Bio Seminar Einat Zalckvar Peroxisomes - From systematic screens to human diseases July 19, 2022 Cell Bio Seminar Daniel Gerlich Chromosome dynamics during the cell cycle July 22, 2022 Cell Bio Seminar Brenda Schulman Unfolding mysteries of cullin-RING E3 ubiquitin ligases -
2020-2021
DATE SPEAKER TALK TITLE Feb 17, 2021 Shenhav Cohen, PhD Structural and Metabolic Control of Cell Size: New Concepts in Muscle Biology Mar 09, 2021 Andrea I McClatchey, PhD Cell polarity in morphogenesis and tumorigenesis -
2019-2020
DATE SPEAKER TALK TITLE Mar 23, 2020 Shasha Chong, PhD Illuminating the dark proteome that regulates gene transcription by live-cell single-molecule imaging Mar 5, 2020 Nora Kory, PhD Mitochondrial transporters and cell metabolism Mar 2, 2020 Lindsay Case, PhD Protein phase separation regulates transmembrane signaling Feb 27, 2020 Lucas Farnung, PhD Barriers to transcription Feb 25, 2020 Meng-meng Fu, PhD Building the Oligodendrocyte: Mechanisms of Acentrosomal Microtubule Nucleation and mRNA Transport Feb 14, 2020 Anna Greka, MD, PhD TMED9 and protein quality control: implications for toxic proteinopathies Feb 3, 2020 Alwin Köhler, MD The role of liquid-liquid phase separation in nuclear ubiquitin signaling Jan 17, 2020 Hermann Steller, PhD Life without aggregates: regulated protein degradation in neuronal function and neurodegenerative diseases Nov 21, 2019 Oliver Bell, PhD Maintenance of mESC identity by Polycomb Repressive Complexes Nov 13, 2019 Suzanne Hoppins Understanding the mitochondrial outer membrane fusion machine Sep 27, 2019 Junjie Hu, PhD Membrane fusion mediated by dynamin-like proteins Sep 20, 2019 Benjamin Ohlstein, MD, PhD Stem Cell Replacement in the Intestine: You Can Go Home Again Sep 13, 2019 Ramesh Nayak, PhD Peer Review of Research Grant applications with the review procedure of R01, R03, R15, R21, R34, P01, P50, Small Business (SBIR) and F32 postdoctoral applications and the definition of Criteria and Consideration for Research Project Grant Critiques at NIH Sep 6, 2019 Sara Rossana Zanivan, PhD Cancer associated fibroblasts: the architects of the tumour stroma Sep 3, 2019 Bernd Bukau, PhD Mechanism of amyloid disintegration by the Hsp70 chaperone network -
2018-2019
DATE SPEAKER TALK TITLE Nov 1, 2018 Steeve Boulant, PhD Clathrin-coated plaques regulate cell migration by identifying topographical cues left by focal adhesion in the extracellular matrix Nov 16, 2018 Sabine Petry, PhD Molecular insight into microtubule nucleation Dec 17, 2018 Radhika Subramanian, PhD Building micron-scale cellular structures from protein building blocks Jan 29, 2019 Simon Wing, MD Modulation of metabolism and glucocorticoid signaling by the USP19 deubiquitinating enzyme Feb 20, 2019 Alexander I. Sobolevsky, PhD Structural and functional studies of vanilloid subtype TRP channels Mar 1, 2019 Ivan Dikic, MD, PhD Unconventional serine ubiquitination and ER remodeling Mar 29, 2019 Jorge Ruas, PhD Regulation of tryptophan-kynurenine metabolism by exercised muscle: from energy metabolism to mental health Apr 17, 2019 Julie Mahamid, PhD Molecular Views into Cellular Function by in-cell Cryo-Electron Tomography Apr 30, 2019 Yifat Merbl, PhD Proteasome Footprinting: Global views of degradation May 28, 2019 Alvaro Martinez del Pozo, PhD The sphingomyelin-cholesterol interaction behind the metamorphosis driving a water-soluble protein into the membrane May 29, 2019 Brendan Canning, PhD Neural encoding mechanisms in cough Jun 10, 2019 Jamie Blaza, PhD Mammalian respiratory complex I through the lens of cryoEM Jul 1, 2019 Eunyong Park, PhD Structure and function of the mitochondrial protein import channel TOM complex Jul 18, 2019 Thomas Misgeld, MD Dynamics and diversity of mitochondria in the mammalian nervous system Aug 2, 2019 Mohan Balasubramanian, PhD Reconstituting eukaryotic cytokinesis Aug 9, 2019 Liang Feng, PhD Structure, dynamics and mechanism of SWEET sugar transporters -
2017-2018
DATE SPEAKER TALK TITLE Sep 20, 2017 Kapil Ramachandran A neuronal-specific plasma membrane proteasome complex degrades nascent polypeptides into extracellular signaling peptides Sep 27, 2017 Ingrid Wertz, MD, PhD USP7 inhibitors reveal deubiquitinase enzymology and cell biology mechanisms Nov 2, 2017 Miratul Muqit MB,ChB, PhD PINK1 kinase signalling pathways in Parkinson's disease Nov 13, 2017 Yukio Fujiki, PhD Peroxisome homeostasis: physiology, biogenesis, and disorders Nov 21, 2017 David J Pagliarini, PhD Defining mitochondrial protein function through systems biochemistry Dec 13, 2017 Vikram Khurana, MD, PhD Genetic and spatial dissection of proteotoxicities from yeast to human neurons Jan 22, 2018 Thomas Kornberg, PhD Contact-dependent cell-cell signaling essential for development and cancer Feb 16, 2018 Jesus Perez-Gil, PhD Molecular machineries and the assembly of membrane conductive networks at the respiratory air-liquid interface Feb 28, 2018 Ru Gunawardane, PhD Using CRISPR/Cas9 and live imaging to model stem cell organization and dynamics Mar 9, 2018 Alwin Köhler, MD Lipid storage at the inner nuclear membrane May 11, 2018 Ron Vale, PhD RNA aggregation and neurodegeneration May 16, 2018 Russell Jones, PhD Visualizing T cell metabolism in vivo: New insights using metabolomics Jun 15, 2018 Eva Hoffmann, PhD Genome Diversification, Chromosome Segregation and Reproductive Aging in Human Females Jun 20, 2018 Bil Clemons Structural insights into the targeting of tail-anchored membrane proteins to the ER Jul 3, 2018 Ron Kopito Parallel genome-wide CRISPR analysis identifies a role for heterotypic ubiquitin chains in ERAD Jul 3, 2018 Bert van den Berg, PhD Porins and pedal bins Jul 16, 2018 Christian Klambt, PhD Glial Barriers and Behavior in Drosophila Jul 19, 2018 Nicolas Thomä, PhD Ubiquitination for a good cause - Understanding CRL4 ubiquitin ligases -
2016-2017
DATE SPEAKER TALK TITLE Sep 27, 2016 Rosanna Piccirillo, PhD Activation of the SDF1/CXCR4 pathway retards muscle atrophy during cancer cachexia Nov 2, 2016 Vivek Malhotra Building blocks and scaffolds controlling the size of transport carriers for collagen and chylomicron secretion Jan 11, 2017 Manuel Thery, PhD Microtubule rejuvenation Jan 25, 2017 Michele Mishto, PhD & Juliane Liepe, PhD I. Proteasome-catalyzed peptide splicing and its biological implications II. From in silico to the clinic: methods to study proteasome-catalysed peptide splicing Mar 3, 2017 James Nathan, MD, PhD Using human forward genetic screens to explore the metabolic control of oxygen sensing enzymes Mar 29, 2017 Luca Scorrano, MD, PhD Mitochondrial dynamics: back to where we started Apr 13, 2017 Chiara Zurzolo, MD, PhD, Tunneling nanotubes: mechanism of formation and role in the intercellular spreading of prion-like aggregates in neurodegenerative diseases Apr 24, 2017 Cole Haynes, PhD Mitochondrial stress responses, innate immunity and toxic genomes May 1, 2017 David Rubinsztein, MD, PhD, Autophagy and Neurodegeneration Jun 5, 2017 Billy Tsai How a non-enveloped virus penetrates a biological membrane to cause infection Jul 7, 2017 Zuzana Storchova, PhD Aneuploidy in human cells: from Down’s syndrome to cancer Jul 14, 2017 Ramanujan "Manu" Hegde A new pathway for membrane protein insertion at the ER Aug 3, 2017 Helder Maiato, PhD Chromosome-intrinsic and -extrinsic factors involved in mitotic fidelity -
2015-2016
DATE SPEAKER TALK TITLE Oct 5, 2015 Jean-Paul Vincent PhD Trafficking and regulation of the Wnt signal Oct 21, 2015 Bill Wickner PhD Membrane Fusion works Entirely Differently than You Thought! Oct 23, 2015 Jon Lorsch, PhD Developing a More Productive, Efficient and Sustainable Biomedical Research Enterprise Feb 8, 2016 Dan Kaganovich, Ph.D. Imperfect asymmetry: a mechanism of asymmetric partitioning of aging factors during mitosis in mammalian cells Mar 21, 2016 Johan Auwerx, MD, PhD Cross-species genetic mapping of targets in metabolism and aging Mar 30, 2016 Jason Gestwicki, PhD Targeting Protein-Protein Interactions in the Chaperone Network to Tune Protein Folding Apr 29, 2016 Charles Horn, PhD The shrew guide to neural circuits for vomiting Jun 1, 2016 George J Murphy, PhD Pluripotent stem cell modeling of human disease Jun 22, 2016 David M Smith, PhD The proteasome: an allosteric machine that is corrupted by a common oligimer in neurodegenerative diseases Jul 18, 2016 Christian Schlieker, PhD Molecular insights into the etiology of nuclear envelopathies: implications for protein quality control and cholesterol metabolism Aug 2, 2016 Nadinath Nillegoda, PhD From prokaryotes to eukaryotes: Deciphering the networking code of J- proteins -
2014-2015
DATE SPEAKER TALK TITLE Sep 8, 2014 Peter Juo, PhD Regulation of glutamate receptor trafficking by the ubiquitin signaling system in C. elegans Sep 23, 2014 Karim Mekhail, PhD From spatial genome organization to RNA-DNA hybrid regulation Mar 31, 2015 Marco Sandri, MD Signaling pathways that control protein homeostasis and energy balance in muscle Jun 4, 2015 KJ Patel How endogenous DNA damage corrupts the production of blood Jun 19, 2015 Anne Bertolotti, PhD Surviving protein quality control failure -
2013-2014
DATE SPEAKER TALK TITLE May 13, 2013 Prof Christophe Lamaze Membrane Dynamics and Mechanics in Intracellular Signaling Oct 7, 2013 Anthony Koleske, PhD Adhesion receptor signaling to the cytoskeleton mediates dendrite arbor and dendritic spine stability Nov 15, 2013 Tatsuo Fukagawa, PhD Centromere specification and assembly in vertebrates Nov 22, 2013 Vahid Khoddami, PhD Target profiling and functional analysis of RNA cytosine methyltransferases Jan 29, 2014 Alejandro Buschiazo, PhD Novel insights into bacterial signaling: the 'one sequence - multiple structures' perspective Jan 31, 2014 Steven Finkbeiner, MD, PhD Insights into neurodegenerative disease gained from single cell analysis Jul 8, 2014 Andreas Matouschek, PhD Protein targeting to the proteasome: is there a second code? Jul 18, 2014 Hiten Madhani, MD, PhD Polycomb/PRC2 in the yeast Cryptococcus neoformans: insights into the control H3K27 methylation
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