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2023-2024
DATE SPEAKER TALK TITLE Dec 13, 2023 David Glass, MD Age-related molecular mechanisms leading to age-related disease Jan 31, 2024 Li-Huei Tsai, PhD Using multi-omic dissection of human brain tissue and IPSC derived brain cell models to understand the pathophysiology of Alzheimer’s disease Mar 6, 2024 Ben Ebert, MD, PhD Targeted protein degradation and novel therapeutics -
2022-2023
DATE SPEAKER TALK TITLE Oct 19, 2022 Tim Mitchison How does the microtubule drug colchicine work as a medicine? Feb 1, 2023 Len Zon Melanoma Initiation and the Cancer Niche Mar 8, 2023 David Matthew Altshuler Humanizing Drug Discovery Apr 19, 2023 Bill Kaelin Von Hippel-Lindau Disease: Insights into Oxygen Sensing, Protein Degradation, and Cancer May 31, 2023 Anna Greka Dissecting cargo receptor-mediated membrane protein trafficking in health and disease -
2021-2022
DATE SPEAKER TALK TITLE Oct 18, 2021 Chenghua Gu, PhD The Neuro-vascular interactions in the CNS Dec 01, 2021 Myles Brown, MD Essential Cancer Genes and Cistromes Jan 26, 2022 Sekar Kathiresan, MD From reading the genome for risk to rewriting it for cardiovascular health Mar 23, 2022 Joan Brugge, PhD Evolution of Concepts about Oncogenes and Mechanisms of Tumorigenesis May 4, 2022 Rosalind Segal, MD, PhD Cancer, chemotherapy and nerves Jun 27, 2022 Harald Stenmark, PhD Membrane dynamics and cancer Jul 7, 2022 Einat Zalckvar, PhD Peroxisomes - from systematic screens to human diseases Jul 19, 2022 Daniel Gerlich Chromosome dynamics during the cell cycle Jul 22, 2022 Brenda Schulman Unfolding mysteries of cullin-RING E3 ubiquitin ligases Jul 29, 2022 David Komander The activation mechanisms of PINK1 and Parking during mitophagy -
2020-2021
DATE SPEAKER TALK TITLE Oct 14, 2020 Michael Gottesman, MD The Complexity and Relevance of Multidrug Resistance in Cancer Dec 2, 2020 Don W Cleveland, PhD “Designer DNA drug” therapies for neurodegenerative disease: What’s next? Feb 21, 2020 Anthony Letai, MD, PhD Poking mitochondria to choose the right cancer drugs Mar 24, 2021 Stephen J Elledge, PhD Spying on the immune system May 5, 2021 Barbara B Kahn, MD Mechanisms by which adipose tissue regulates metabolic health and disease -
2019-2020
DATE SPEAKER TALK TITLE Nov 6, 2019 Patricia A D'Amore, PhD, MBA VEGF, Angiogenesis and Macular Degeneration Dec 11, 2019 David E. Fisher, MD, PhD Lessons for melanoma therapeutics based on its unique pathogenesis Feb 12, 2020 Denisa Wagner, PhD Inflammation and thrombosis, if it does not save you, it will kill you Apr 1, 2020 Stephen Liberles, PhD Regulation of body functions by the vagus nerve -
2018-2019
DATE SPEAKER TALK TITLE Dec 5, 2018 Dennis J Selkoe, MD Cell Biology of Alzheimer’s and Parkinson’s Diseases Reveals New Therapeutic Targets Jan 16, 2019 David Sinclair, PhD Advances in reprogramming to turn back the aging clock Mar 13, 2019 Morris Birnbaum, MD, PhD Pathophysiology and Therapeutic Strategies for Metabolic Disease May 8, 2019 Stuart Orkin, MD Reactivating fetal hemoglobin to treat hemoglobin disorders: genetic and non-genetic approaches May 29, 2019 Richard Ransohoff, MD Neuroinflammation: What is it, how does it contribute to neurological disease? -
2017-2018
DATE SPEAKER TALK TITLE Nov 2, 2017 George Q Daley, PhD A twenty year quest to derive Hematopoietic Stem Cells in vitro Jan 17, 2018 Benjamin Ebert, MD, PhD Therapeutic targeting of ubiquitin ligase activity. Mar 7, 2018 Leslie Leinwand, PhD Myosin myopathies: pathogenesis and potential therapies Apr 18, 2018 Lee Rubin, PhD Looking at Neurological Disorders from Different Perspectives May 30, 2018 Frank Slack, PhD Translating ncRNA discoveries to personalized RNA medicine for cancer -
2016-2017
DATE SPEAKER TALK TITLE Nov 16, 2016 Gary Borisy, PhD Mapping the Microbiome at the Micron Scale Jan 18, 2017 Junying Yuan, PhD Necroptosis: from basic cell biology to human clinical studies Mar 8, 2017 Leonard Zon, MD Pathways regulating hematopoietic stem cell self-renewal and migration Apr 12, 2017 Vamsi Mootha, MD Mitochondrial parts, pathways, and pathogenesis May 3, 2017 Peter Libby, MD Inflammation in Atherosclerosis - a Translational Journey -
2015-2016
DATE SPEAKER TALK TITLE Jan 20, 2016 Richard Gregory, PhD Defective RNA metabolism in childhood developmental syndromes Feb 17, 2016 Monty Krieger, PhD Heart Attacks and Strokes: The Cholesterol Connection and Lipoprotein Receptors Mar 16, 2016 Isaac Chiu, PhD Neuro-immune interactions in pain and host defense Apr 27, 2016 Arlene Sharp, MD, PhD Cancer immunotherapy: The PD-1 pathway from discover to translation Jun 1, 2016 Shalender Bhasin, MD Muscle in a Bottle: The Pharmaceutical Applications of Androgen Biology -
2014-2015
DATE SPEAKER TALK TITLE Dec 17, 2014 Thomas Schwarz, PhD Mar 25, 2015 Richard T. Lee, MD Apr 22, 2015 Ulrich von Andrian, MD, PhD Career decisions: How T cells remember pathogens May 20, 2015 Kim Lewis, PhD Finding antibiotics to cure chronic infections -
2013-2014
DATE SPEAKER TALK TITLE Jan 16, 2013 Charles Serhan, PhD Resolving Inflammation: Elucidation of the Mediators and their Therapeutic Potential Mar 20, 2013 David Cohen, MD, PhD START Domain-Mediated Metabolic Regulation Reveals New Therapeutic Targets for Diabetes and Obesity Mar 27, 2013 Benjamin Podbilewicz, PhD Membrane Proteins Mediating Cell-Cell Fusion? May 15, 2013 Joseph Loscalzo, MD, PhD Redox Dysregulation in Vascular Pathobiology Jun 19, 2013 Louis Kunkel, PhD Muscular Dystrophy: From Gene Discovery to Therapy Nov 20, 2013 Brad Lowell, MD, PhD The Neural Wiring Diagram for Hunger: Using Cre/Lox Tools to Discover its Basis Feb 19, 2014 David Scadden, MD Stem cell niche in homeostasis and cancer Mar 19, 2014 David Glass, PhD Molecular causes of skeletal muscle loss and function, and their treatment Apr 16, 2014 Phil Kantoff, MD Prostate Cancer, a Disease of Paradoxes Jun 18, 2014 Connie Cepko, PhD Strategies to prolong vision in inherited forms of blindness
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