2023-2024

DATESPEAKERTALK TITLE
Dec 13, 2023David Glass, MDAge-related molecular mechanisms leading to age-related disease
Jan 31, 2024Li-Huei Tsai, PhDUsing multi-omic dissection of human brain tissue and IPSC derived brain cell models to understand the pathophysiology of Alzheimer’s disease
Mar 6, 2024Ben Ebert, MD, PhDTargeted protein degradation and novel therapeutics

2022-2023

DATESPEAKERTALK TITLE
Oct 19, 2022Tim MitchisonHow does the microtubule drug colchicine work as a medicine?
Feb 1, 2023Len ZonMelanoma Initiation and the Cancer Niche
Mar 8, 2023David Matthew AltshulerHumanizing Drug Discovery
Apr 19, 2023Bill KaelinVon Hippel-Lindau Disease: Insights into Oxygen Sensing, Protein Degradation, and Cancer
May 31, 2023Anna GrekaDissecting cargo receptor-mediated membrane protein trafficking in health and disease

2021-2022

DATESPEAKERTALK TITLE
Oct 18, 2021Chenghua Gu, PhDThe Neuro-vascular interactions in the CNS
Dec 01, 2021Myles Brown, MDEssential Cancer Genes and Cistromes
Jan 26, 2022Sekar Kathiresan, MDFrom reading the genome for risk to rewriting it for cardiovascular health
Mar 23, 2022Joan Brugge, PhDEvolution of Concepts about Oncogenes and Mechanisms of Tumorigenesis
May 4, 2022Rosalind Segal, MD, PhDCancer, chemotherapy and nerves
Jun 27, 2022Harald Stenmark, PhDMembrane dynamics and cancer
Jul 7, 2022Einat Zalckvar, PhDPeroxisomes - from systematic screens to human diseases
Jul 19, 2022Daniel GerlichChromosome dynamics during the cell cycle
Jul 22, 2022Brenda SchulmanUnfolding mysteries of cullin-RING E3 ubiquitin ligases
Jul 29, 2022David KomanderThe activation mechanisms of PINK1 and Parking during mitophagy

2020-2021

DATESPEAKERTALK TITLE
Oct 14, 2020Michael Gottesman, MDThe Complexity and Relevance of Multidrug Resistance in Cancer
Dec 2, 2020Don W Cleveland, PhD“Designer DNA drug” therapies for neurodegenerative disease: What’s next?
Feb 21, 2020Anthony Letai, MD, PhDPoking mitochondria to choose the right cancer drugs
Mar 24, 2021Stephen J Elledge, PhDSpying on the immune system
May 5, 2021Barbara B Kahn, MDMechanisms by which adipose tissue regulates metabolic health and disease

2019-2020

DATESPEAKERTALK TITLE
Nov 6, 2019Patricia A D'Amore, PhD, MBAVEGF, Angiogenesis and Macular Degeneration
Dec 11, 2019David E. Fisher, MD, PhDLessons for melanoma therapeutics based on its unique pathogenesis
Feb 12, 2020Denisa Wagner, PhDInflammation and thrombosis, if it does not save you, it will kill you
Apr 1, 2020Stephen Liberles, PhDRegulation of body functions by the vagus nerve

2018-2019

DATESPEAKERTALK TITLE
Dec 5, 2018Dennis J Selkoe, MDCell Biology of Alzheimer’s and Parkinson’s Diseases Reveals New Therapeutic Targets
Jan 16, 2019David Sinclair, PhDAdvances in reprogramming to turn back the aging clock
Mar 13, 2019Morris Birnbaum, MD, PhDPathophysiology and Therapeutic Strategies for Metabolic Disease
May 8, 2019Stuart Orkin, MDReactivating fetal hemoglobin to treat hemoglobin disorders: genetic and non-genetic approaches
May 29, 2019Richard Ransohoff, MDNeuroinflammation: What is it, how does it contribute to neurological disease?

2017-2018

DATESPEAKERTALK TITLE
Nov 2, 2017George Q Daley, PhDA twenty year quest to derive Hematopoietic Stem Cells in vitro
Jan 17, 2018Benjamin Ebert, MD, PhDTherapeutic targeting of ubiquitin ligase activity.
Mar 7, 2018Leslie Leinwand, PhDMyosin myopathies: pathogenesis and potential therapies
Apr 18, 2018Lee Rubin, PhDLooking at Neurological Disorders from Different Perspectives
May 30, 2018Frank Slack, PhDTranslating ncRNA discoveries to personalized RNA medicine for cancer

2016-2017

DATESPEAKERTALK TITLE
Nov 16, 2016Gary Borisy, PhDMapping the Microbiome at the Micron Scale
Jan 18, 2017Junying Yuan, PhDNecroptosis: from basic cell biology to human clinical studies
Mar 8, 2017Leonard Zon, MDPathways regulating hematopoietic stem cell self-renewal and migration
Apr 12, 2017Vamsi Mootha, MDMitochondrial parts, pathways, and pathogenesis
May 3, 2017Peter Libby, MDInflammation in Atherosclerosis - a Translational Journey

2015-2016

DATESPEAKERTALK TITLE
Jan 20, 2016Richard Gregory, PhDDefective RNA metabolism in childhood developmental syndromes
Feb 17, 2016Monty Krieger, PhDHeart Attacks and Strokes: The Cholesterol Connection and Lipoprotein Receptors
Mar 16, 2016Isaac Chiu, PhDNeuro-immune interactions in pain and host defense
Apr 27, 2016Arlene Sharp, MD, PhDCancer immunotherapy: The PD-1 pathway from discover to translation
Jun 1, 2016Shalender Bhasin, MDMuscle in a Bottle: The Pharmaceutical Applications of Androgen Biology

2014-2015

DATESPEAKERTALK TITLE
Dec 17, 2014Thomas Schwarz, PhD
Mar 25, 2015Richard T. Lee, MD
Apr 22, 2015Ulrich von Andrian, MD, PhDCareer decisions: How T cells remember pathogens
May 20, 2015Kim Lewis, PhDFinding antibiotics to cure chronic infections

2013-2014

DATESPEAKERTALK TITLE
Jan 16, 2013Charles Serhan, PhDResolving Inflammation: Elucidation of the Mediators and their Therapeutic Potential
Mar 20, 2013David Cohen, MD, PhDSTART Domain-Mediated Metabolic Regulation Reveals New Therapeutic Targets for Diabetes and Obesity
Mar 27, 2013Benjamin Podbilewicz, PhDMembrane Proteins Mediating Cell-Cell Fusion?
May 15, 2013Joseph Loscalzo, MD, PhDRedox Dysregulation in Vascular Pathobiology
Jun 19, 2013Louis Kunkel, PhDMuscular Dystrophy: From Gene Discovery to Therapy
Nov 20, 2013Brad Lowell, MD, PhDThe Neural Wiring Diagram for Hunger: Using Cre/Lox Tools to Discover its Basis
Feb 19, 2014David Scadden, MDStem cell niche in homeostasis and cancer
Mar 19, 2014David Glass, PhDMolecular causes of skeletal muscle loss and function, and their treatment
Apr 16, 2014Phil Kantoff, MDProstate Cancer, a Disease of Paradoxes
Jun 18, 2014Connie Cepko, PhDStrategies to prolong vision in inherited forms of blindness