Stephen Liberles
Stephen Liberles, Ph.D.
Professor of Cell Biology (HMS)
HHMI Investigator
Member: Harvard Program in Neuroscience

Stephen Liberles, Ph.D. is a Professor and HHMI Investigator in the Cell Biology Department at Harvard Medical School. Dr. Liberles received an undergraduate degree in Chemistry from Harvard in 1994, and a Ph.D. in Chemistry and Chemical Biology from Harvard in 1999, working in the lab of Stuart Schreiber. He then performed post-doctoral work in the lab of Linda Buck, first at Harvard Medical School and then at the Fred Hutchinson Cancer Research Center in Seattle.

The Liberles Lab focuses on the molecular neuroscience of sensory systems, including olfaction, pheromone sensing, taste, and internal organ senses of the vagus nerve. Some discoveries from his lab include characterizing non-classical families of olfactory receptors, odors and pheromones that stimulate innate behaviors, vagus nerve cell types that selectively control autonomic physiology, and mechanisms underlying sensation within internal organs, including airway stretch and changes in aortic blood pressure.

Harvard Medical School

Dept. of Cell Biology, LHRRB 601A

240 Longwood Avenue

Boston, MA 02115

Lab phone: 617-432-7283

Lab fax: 617-432-7285

Prox2 and Runx3 vagal sensory neurons regulate esophageal motility.
Authors: Authors: Lowenstein ED, Ruffault PL, Misios A, Osman KL, Li H, Greenberg RS, Thompson R, Song K, Dietrich S, Li X, Vladimirov N, Woehler A, Brunet JF, Zampieri N, Kühn R, Liberles SD, Jia S, Lewin GR, Rajewsky N, Lever TE, Birchmeier C.
Neuron
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Structural basis of amine odorant perception by a mammal olfactory receptor.
Authors: Authors: Guo L, Cheng J, Lian S, Liu Q, Lu Y, Zheng Y, Zhu K, Zhang M, Kong Y, Zhang C, Rong N, Zhuang Y, Fang G, Jiang J, Zhang T, Han X, Liu Z, Xia M, Liu S, Zhang L, Liberles SD, Yu X, Xu Y, Yang F, Li Q, Sun JP.
Nature
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An airway-to-brain sensory pathway mediates influenza-induced sickness.
Authors: Authors: Bin NR, Prescott SL, Horio N, Wang Y, Chiu IM, Liberles SD.
Nature
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Enteroendocrine cell lineages that differentially control feeding and gut motility.
Authors: Authors: Hayashi M, Kaye JA, Douglas ER, Joshi NR, Gribble FM, Reimann F, Liberles SD.
Elife
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Publisher Correction: A brainstem map for visceral sensations.
Authors: Authors: Ran C, Boettcher JC, Kaye JA, Gallori CE, Liberles SD.
Nature
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A brainstem map for visceral sensations.
Authors: Authors: Ran C, Boettcher JC, Kaye JA, Gallori CE, Liberles SD.
Nature
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A brainstem circuit for nausea suppression.
Authors: Authors: Zhang C, Vincelette LK, Reimann F, Liberles SD.
Cell Rep
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Internal senses of the vagus nerve.
Authors: Authors: Prescott SL, Liberles SD.
Neuron
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Highly selective brain-to-gut communication via genetically defined vagus neurons.
Authors: Authors: Tao J, Campbell JN, Tsai LT, Wu C, Liberles SD, Lowell BB.
Neuron
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Coordination of two enhancers drives expression of olfactory trace amine-associated receptors.
Authors: Authors: Fei A, Wu W, Tan L, Tang C, Xu Z, Huo X, Bao H, Kong Y, Johnson M, Hartmann G, Talay M, Yang C, Riegler C, Herrera KJ, Engert F, Xie XS, Barnea G, Liberles SD, Yang H, Li Q.
Nat Commun
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