Stephen Liberles
Stephen Liberles, Ph.D.
Professor of Cell Biology (HMS)
HHMI Investigator
Member: Harvard Program in Neuroscience

Stephen Liberles, Ph.D. is a Professor and HHMI Investigator in the Cell Biology Department at Harvard Medical School. Dr. Liberles received an undergraduate degree in Chemistry from Harvard in 1994, and a Ph.D. in Chemistry and Chemical Biology from Harvard in 1999, working in the lab of Stuart Schreiber. He then performed post-doctoral work in the lab of Linda Buck, first at Harvard Medical School and then at the Fred Hutchinson Cancer Research Center in Seattle.

The Liberles Lab focuses on the molecular neuroscience of sensory systems, including olfaction, pheromone sensing, taste, and internal organ senses of the vagus nerve. Some discoveries from his lab include characterizing non-classical families of olfactory receptors, odors and pheromones that stimulate innate behaviors, vagus nerve cell types that selectively control autonomic physiology, and mechanisms underlying sensation within internal organs, including airway stretch and changes in aortic blood pressure.


Harvard Medical School

Dept. of Cell Biology, LHRRB 601A

240 Longwood Avenue

Boston, MA 02115

Lab phone: 617-432-7283

Lab fax: 617-432-7285

Internal senses of the vagus nerve.
Authors: Authors: Prescott SL, Liberles SD.
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Highly selective brain-to-gut communication via genetically defined vagus neurons.
Authors: Authors: Tao J, Campbell JN, Tsai LT, Wu C, Liberles SD, Lowell BB.
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Coordination of two enhancers drives expression of olfactory trace amine-associated receptors.
Authors: Authors: Fei A, Wu W, Tan L, Tang C, Xu Z, Huo X, Bao H, Kong Y, Johnson M, Hartmann G, Talay M, Yang C, Riegler C, Herrera KJ, Engert F, Xie XS, Barnea G, Liberles SD, Yang H, Li Q.
Nat Commun
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Periphery signals generated by Piezo-mediated stomach stretch and Neuromedin-mediated glucose load regulate the Drosophila brain nutrient sensor.
Authors: Authors: Oh Y, Lai JS, Min S, Huang HW, Liberles SD, Ryoo HD, Suh GSB.
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Hunger enhances food-odour attraction through a neuropeptide Y spotlight.
Authors: Authors: Horio N, Liberles SD.
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Control of feeding by Piezo-mediated gut mechanosensation in Drosophila.
Authors: Authors: Min S, Oh Y, Verma P, Whitehead SC, Yapici N, Van Vactor D, Suh GS, Liberles S.
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Area Postrema Cell Types that Mediate Nausea-Associated Behaviors.
Authors: Authors: Zhang C, Kaye JA, Cai Z, Wang Y, Prescott SL, Liberles SD.
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An Airway Protection Program Revealed by Sweeping Genetic Control of Vagal Afferents.
Authors: Authors: Prescott SL, Umans BD, Williams EK, Brust RD, Liberles SD.
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Arterial Baroreceptors Sense Blood Pressure through Decorated Aortic Claws.
Authors: Authors: Min S, Chang RB, Prescott SL, Beeler B, Joshi NR, Strochlic DE, Liberles SD.
Cell Rep
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Defined Paraventricular Hypothalamic Populations Exhibit Differential Responses to Food Contingent on Caloric State.
Authors: Authors: Li C, Navarrete J, Liang-Guallpa J, Lu C, Funderburk SC, Chang RB, Liberles SD, Olson DP, Krashes MJ.
Cell Metab
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